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Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation.
van Elsas A, Hurwitz AA, Allison JP. van Elsas A, et al. Among authors: allison jp. J Exp Med. 1999 Aug 2;190(3):355-66. doi: 10.1084/jem.190.3.355. J Exp Med. 1999. PMID: 10430624 Free PMC article.
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy.
van Elsas A, Sutmuller RP, Hurwitz AA, Ziskin J, Villasenor J, Medema JP, Overwijk WW, Restifo NP, Melief CJ, Offringa R, Allison JP. van Elsas A, et al. Among authors: allison jp. J Exp Med. 2001 Aug 20;194(4):481-9. doi: 10.1084/jem.194.4.481. J Exp Med. 2001. PMID: 11514604 Free PMC article.
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.
Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, Allison JP, Toes RE, Offringa R, Melief CJ. Sutmuller RP, et al. Among authors: allison jp. J Exp Med. 2001 Sep 17;194(6):823-32. doi: 10.1084/jem.194.6.823. J Exp Med. 2001. PMID: 11560997 Free PMC article.
CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems.
Gregor PD, Wolchok JD, Ferrone CR, Buchinshky H, Guevara-Patiño JA, Perales MA, Mortazavi F, Bacich D, Heston W, Latouche JB, Sadelain M, Allison JP, Scher HI, Houghton AN. Gregor PD, et al. Among authors: allison jp. Vaccine. 2004 Apr 16;22(13-14):1700-8. doi: 10.1016/j.vaccine.2003.10.048. Vaccine. 2004. PMID: 15068853
364 results