Brunsveld L - Search Results

1

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.

Guo Z, Wu YW, Das D, Delon C, Cramer J, Yu S, Thuns S, Lupilova N, Waldmann H, Brunsveld L, Goody RS, Alexandrov K, Blankenfeldt W. Guo Z, et al. Among authors: brunsveld l. EMBO J. 2008 Sep 17;27(18):2444-56. doi: 10.1038/emboj.2008.164. Epub 2008 Aug 28. EMBO J. 2008. PMID: 18756270 Free PMC article.

2

Synthesis of functionalized rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligation.

Brunsveld L, Watzke A, Durek T, Alexandrov K, Goody RS, Waldmann H. Brunsveld L, et al. Chemistry. 2005 Apr 22;11(9):2756-72. doi: 10.1002/chem.200401041. Chemistry. 2005. PMID: 15729676

3

Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases.

Watzke A, Brunsveld L, Durek T, Alexandrov K, Rak A, Goody RS, Waldmann H. Watzke A, et al. Among authors: brunsveld l. Org Biomol Chem. 2005 Apr 7;3(7):1157-64. doi: 10.1039/b417573e. Epub 2005 Feb 24. Org Biomol Chem. 2005. PMID: 15785799 Review.

4

Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling.

Pylypenko O, Rak A, Durek T, Kushnir S, Dursina BE, Thomae NH, Constantinescu AT, Brunsveld L, Watzke A, Waldmann H, Goody RS, Alexandrov K. Pylypenko O, et al. Among authors: brunsveld l. EMBO J. 2006 Jan 11;25(1):13-23. doi: 10.1038/sj.emboj.7600921. Epub 2006 Jan 5. EMBO J. 2006. PMID: 16395334 Free PMC article.

5

Lipidated ras and rab peptides and proteins--synthesis, structure, and function.

Brunsveld L, Kuhlmann J, Alexandrov K, Wittinghofer A, Goody RS, Waldmann H. Brunsveld L, et al. Angew Chem Int Ed Engl. 2006 Oct 13;45(40):6622-46. doi: 10.1002/anie.200600855. Angew Chem Int Ed Engl. 2006. PMID: 17031879 Review.

6

A synthetic supramolecular construct modulating protein assembly in cells.

Zhang L, Wu Y, Brunsveld L. Zhang L, et al. Among authors: brunsveld l. Angew Chem Int Ed Engl. 2007;46(11):1798-802. doi: 10.1002/anie.200604222. Angew Chem Int Ed Engl. 2007. PMID: 17450607 No abstract available.

7

Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase.

Wu YW, Alexandrov K, Brunsveld L. Wu YW, et al. Among authors: brunsveld l. Nat Protoc. 2007;2(11):2704-11. doi: 10.1038/nprot.2007.401. Nat Protoc. 2007. PMID: 18007605

8

Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction.

Triola G, Brunsveld L, Waldmann H. Triola G, et al. Among authors: brunsveld l. J Org Chem. 2008 May 2;73(9):3646-9. doi: 10.1021/jo800198s. Epub 2008 Apr 1. J Org Chem. 2008. PMID: 18376863

9

Membrane binding of lipidated Ras peptides and proteins--the structural point of view.

Brunsveld L, Waldmann H, Huster D. Brunsveld L, et al. Biochim Biophys Acta. 2009 Jan;1788(1):273-88. doi: 10.1016/j.bbamem.2008.08.006. Epub 2008 Aug 15. Biochim Biophys Acta. 2009. PMID: 18771652 Free article. Review.

10

Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein.

Alexander M, Gerauer M, Pechlivanis M, Popkirova B, Dvorsky R, Brunsveld L, Waldmann H, Kuhlmann J. Alexander M, et al. Among authors: brunsveld l. Chembiochem. 2009 Jan 5;10(1):98-108. doi: 10.1002/cbic.200800275. Chembiochem. 2009. PMID: 18846587

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