van Lohuizen M - Search Results

1

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

Taghavi P, Verhoeven E, Jacobs JJ, Lambooij JP, Stortelers C, Tanger E, Moolenaar WH, van Lohuizen M. Taghavi P, et al. Among authors: van lohuizen m. Oncogene. 2008 Nov 20;27(54):6806-16. doi: 10.1038/onc.2008.294. Epub 2008 Sep 1. Oncogene. 2008. PMID: 18762810

2

Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex.

Alkema MJ, Bronk M, Verhoeven E, Otte A, van 't Veer LJ, Berns A, van Lohuizen M. Alkema MJ, et al. Among authors: van t veer lj, van lohuizen m. Genes Dev. 1997 Jan 15;11(2):226-40. doi: 10.1101/gad.11.2.226. Genes Dev. 1997. PMID: 9009205 Free article.

3

Pertubation of B and T cell development and predisposition to lymphomagenesis in Emu Bmi1 transgenic mice require the Bmi1 RING finger.

Alkema MJ, Jacobs H, van Lohuizen M, Berns A. Alkema MJ, et al. Among authors: van lohuizen m. Oncogene. 1997 Aug 18;15(8):899-910. doi: 10.1038/sj.onc.1201262. Oncogene. 1997. PMID: 9285685

4

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

Alkema MJ, Jacobs J, Voncken JW, Jenkins NA, Copeland NG, Satijn DP, Otte AP, Berns A, van Lohuizen M. Alkema MJ, et al. Among authors: van lohuizen m. J Mol Biol. 1997 Nov 14;273(5):993-1003. doi: 10.1006/jmbi.1997.1372. J Mol Biol. 1997. PMID: 9367786

5

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. Jacobs JJ, et al. Among authors: van lohuizen m. Nature. 1999 Jan 14;397(6715):164-8. doi: 10.1038/16476. Nature. 1999. PMID: 9923679

6

Cellular memory of transcriptional states by Polycomb-group proteins.

Jacobs JJ, van Lohuizen M. Jacobs JJ, et al. Among authors: van lohuizen m. Semin Cell Dev Biol. 1999 Apr;10(2):227-35. doi: 10.1006/scdb.1999.0304. Semin Cell Dev Biol. 1999. PMID: 10441076 Review.

7

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Jacobs JJ, et al. Among authors: van lohuizen m. Genes Dev. 1999 Oct 15;13(20):2678-90. doi: 10.1101/gad.13.20.2678. Genes Dev. 1999. PMID: 10541554 Free PMC article.

8

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, van Welsem T, van de Vijver MJ, Koh EY, Daley GQ, van Lohuizen M. Jacobs JJ, et al. Among authors: van welsem t, van de vijver mj, van lohuizen m. Nat Genet. 2000 Nov;26(3):291-9. doi: 10.1038/81583. Nat Genet. 2000. PMID: 11062467

9

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

Lingbeek ME, Jacobs JJ, van Lohuizen M. Lingbeek ME, et al. Among authors: van lohuizen m. J Biol Chem. 2002 Jul 19;277(29):26120-7. doi: 10.1074/jbc.M200403200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000749 Free article.

10

Polycomb repression: from cellular memory to cellular proliferation and cancer.

Jacobs JJ, van Lohuizen M. Jacobs JJ, et al. Among authors: van lohuizen m. Biochim Biophys Acta. 2002 Jun 21;1602(2):151-61. doi: 10.1016/s0304-419x(02)00052-5. Biochim Biophys Acta. 2002. PMID: 12020801 Review.

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