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Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters.
Wargon V, Riggio M, Giulianelli S, Sequeira GR, Rojas P, May M, Polo ML, Gorostiaga MA, Jacobsen B, Molinolo A, Novaro V, Lanari C. Wargon V, et al. Among authors: gorostiaga ma. Int J Cancer. 2015 Jun 1;136(11):2680-92. doi: 10.1002/ijc.29304. Epub 2014 Nov 12. Int J Cancer. 2015. PMID: 25363551 Free PMC article.
FGF2 induces breast cancer growth through ligand-independent activation and recruitment of ERα and PRBΔ4 isoform to MYC regulatory sequences.
Giulianelli S, Riggio M, Guillardoy T, Pérez Piñero C, Gorostiaga MA, Sequeira G, Pataccini G, Abascal MF, Toledo MF, Jacobsen BM, Guerreiro AC, Barros A, Novaro V, Monteiro FL, Amado F, Gass H, Abba M, Helguero LA, Lanari C. Giulianelli S, et al. Among authors: gorostiaga ma. Int J Cancer. 2019 Oct 1;145(7):1874-1888. doi: 10.1002/ijc.32252. Epub 2019 Mar 28. Int J Cancer. 2019. PMID: 30843188
Classical membrane progesterone receptors in murine mammary carcinomas: agonistic effects of progestins and RU-486 mediating rapid non-genomic effects.
Bottino MC, Cerliani JP, Rojas P, Giulianelli S, Soldati R, Mondillo C, Gorostiaga MA, Pignataro OP, Calvo JC, Gutkind JS, Panomwat Amornphimoltham, Molinolo AA, Lüthy IA, Lanari C. Bottino MC, et al. Among authors: gorostiaga ma. Breast Cancer Res Treat. 2011 Apr;126(3):621-36. doi: 10.1007/s10549-010-0971-3. Epub 2010 Jun 10. Breast Cancer Res Treat. 2011. PMID: 20535544