Avvaru BS - Search Results

1

Entrapment of carbon dioxide in the active site of carbonic anhydrase II.

Domsic JF, Avvaru BS, Kim CU, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. Domsic JF, et al. Among authors: avvaru bs. J Biol Chem. 2008 Nov 7;283(45):30766-71. doi: 10.1074/jbc.M805353200. Epub 2008 Sep 2. J Biol Chem. 2008. PMID: 18768466 Free PMC article.

2

Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II.

Zheng J, Avvaru BS, Tu C, McKenna R, Silverman DN. Zheng J, et al. Among authors: avvaru bs. Biochemistry. 2008 Nov 18;47(46):12028-36. doi: 10.1021/bi801473w. Epub 2008 Oct 23. Biochemistry. 2008. PMID: 18942852 Free PMC article.

3

Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.

Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Genis C, et al. Among authors: avvaru bs. Biochemistry. 2009 Feb 17;48(6):1322-31. doi: 10.1021/bi802035f. Biochemistry. 2009. PMID: 19170619 Free PMC article.

4

Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network.

Avvaru BS, Busby SA, Chalmers MJ, Griffin PR, Venkatakrishnan B, Agbandje-McKenna M, Silverman DN, McKenna R. Avvaru BS, et al. Biochemistry. 2009 Aug 11;48(31):7365-72. doi: 10.1021/bi9007512. Biochemistry. 2009. PMID: 19583303 Free PMC article.

5

A short, strong hydrogen bond in the active site of human carbonic anhydrase II.

Avvaru BS, Kim CU, Sippel KH, Gruner SM, Agbandje-McKenna M, Silverman DN, McKenna R. Avvaru BS, et al. Biochemistry. 2010 Jan 19;49(2):249-51. doi: 10.1021/bi902007b. Biochemistry. 2010. PMID: 20000378 Free PMC article.

6

Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.

Wagner J, Avvaru BS, Robbins AH, Scozzafava A, Supuran CT, McKenna R. Wagner J, et al. Among authors: avvaru bs. Bioorg Med Chem. 2010 Jul 15;18(14):4873-8. doi: 10.1016/j.bmc.2010.06.028. Epub 2010 Jun 15. Bioorg Med Chem. 2010. PMID: 20598552 Free PMC article.

7

Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II.

Avvaru BS, Arenas DJ, Tu C, Tanner DB, McKenna R, Silverman DN. Avvaru BS, et al. Arch Biochem Biophys. 2010 Oct 1;502(1):53-9. doi: 10.1016/j.abb.2010.07.010. Epub 2010 Jul 14. Arch Biochem Biophys. 2010. PMID: 20637176 Free PMC article.

8

Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.

Pacchiano F, Aggarwal M, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Pacchiano F, et al. Among authors: avvaru bs. Chem Commun (Camb). 2010 Nov 28;46(44):8371-3. doi: 10.1039/c0cc02707c. Epub 2010 Oct 5. Chem Commun (Camb). 2010. PMID: 20922253

9

Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II.

Mikulski R, Avvaru BS, Tu C, Case N, McKenna R, Silverman DN. Mikulski R, et al. Among authors: avvaru bs. Arch Biochem Biophys. 2011 Feb 15;506(2):181-7. doi: 10.1016/j.abb.2010.12.004. Epub 2010 Dec 9. Arch Biochem Biophys. 2011. PMID: 21145876 Free PMC article.

10

Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.

Mikulski R, West D, Sippel KH, Avvaru BS, Aggarwal M, Tu C, McKenna R, Silverman DN. Mikulski R, et al. Among authors: avvaru bs. Biochemistry. 2013 Jan 8;52(1):125-31. doi: 10.1021/bi301099k. Epub 2012 Dec 18. Biochemistry. 2013. PMID: 23215152 Free PMC article.

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