Côté JF - Search Results

1

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.

Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF. Komander D, et al. Among authors: cote jf. Mol Biol Cell. 2008 Nov;19(11):4837-51. doi: 10.1091/mbc.e08-04-0345. Epub 2008 Sep 3. Mol Biol Cell. 2008. PMID: 18768751 Free PMC article.

2

A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.

Côté JF, Motoyama AB, Bush JA, Vuori K. Côté JF, et al. Nat Cell Biol. 2005 Aug;7(8):797-807. doi: 10.1038/ncb1280. Epub 2005 Jul 17. Nat Cell Biol. 2005. PMID: 16025104 Free PMC article.

3

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways.

Côté JF, Vuori K. Côté JF, et al. Trends Cell Biol. 2007 Aug;17(8):383-93. doi: 10.1016/j.tcb.2007.05.001. Epub 2007 Aug 31. Trends Cell Biol. 2007. PMID: 17765544 Free PMC article. Review.

4

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo.

Laurin M, Fradet N, Blangy A, Hall A, Vuori K, Côté JF. Laurin M, et al. Among authors: cote jf. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15446-51. doi: 10.1073/pnas.0805546105. Epub 2008 Sep 26. Proc Natl Acad Sci U S A. 2008. PMID: 18820033 Free PMC article.

5

Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs).

Premkumar L, Bobkov AA, Patel M, Jaroszewski L, Bankston LA, Stec B, Vuori K, Côté JF, Liddington RC. Premkumar L, et al. Among authors: cote jf. J Biol Chem. 2010 Apr 23;285(17):13211-22. doi: 10.1074/jbc.M110.102517. Epub 2010 Feb 18. J Biol Chem. 2010. PMID: 20167601 Free PMC article.

6

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

Sanematsu F, Hirashima M, Laurin M, Takii R, Nishikimi A, Kitajima K, Ding G, Noda M, Murata Y, Tanaka Y, Masuko S, Suda T, Meno C, Côté JF, Nagasawa T, Fukui Y. Sanematsu F, et al. Among authors: cote jf. Circ Res. 2010 Oct 29;107(9):1102-5. doi: 10.1161/CIRCRESAHA.110.223388. Epub 2010 Sep 9. Circ Res. 2010. PMID: 20829512 Free PMC article.

7

An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling.

Patel M, Margaron Y, Fradet N, Yang Q, Wilkes B, Bouvier M, Hofmann K, Côté JF. Patel M, et al. Among authors: cote jf. Curr Biol. 2010 Nov 23;20(22):2021-7. doi: 10.1016/j.cub.2010.10.028. Epub 2010 Oct 28. Curr Biol. 2010. PMID: 21035343 Free PMC article.

8

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.

Vives V, Laurin M, Cres G, Larrousse P, Morichaud Z, Noel D, Côté JF, Blangy A. Vives V, et al. Among authors: cote jf. J Bone Miner Res. 2011 May;26(5):1099-110. doi: 10.1002/jbmr.282. J Bone Miner Res. 2011. PMID: 21542010 Free PMC article.

9

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.

Patel M, Chiang TC, Tran V, Lee FJ, Côté JF. Patel M, et al. Among authors: cote jf. J Biol Chem. 2011 Nov 11;286(45):38969-79. doi: 10.1074/jbc.M111.274191. Epub 2011 Sep 19. J Biol Chem. 2011. PMID: 21930703 Free PMC article.

10

Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex.

Patel M, Pelletier A, Côté JF. Patel M, et al. Among authors: cote jf. Small GTPases. 2011 Sep;2(5):268-275. doi: 10.4161/sgtp.2.5.17716. Epub 2011 Sep 1. Small GTPases. 2011. PMID: 22292130 Free PMC article.

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