Fradet N - Search Results

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An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.

Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF. Komander D, et al. Among authors: fradet n. Mol Biol Cell. 2008 Nov;19(11):4837-51. doi: 10.1091/mbc.e08-04-0345. Epub 2008 Sep 3. Mol Biol Cell. 2008. PMID: 18768751 Free PMC article.

An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling.

Patel M, Margaron Y, Fradet N, Yang Q, Wilkes B, Bouvier M, Hofmann K, Côté JF. Patel M, et al. Among authors: fradet n. Curr Biol. 2010 Nov 23;20(22):2021-7. doi: 10.1016/j.cub.2010.10.028. Epub 2010 Oct 28. Curr Biol. 2010. PMID: 21035343 Free PMC article.

ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.

Margaron Y, Fradet N, Côté JF. Margaron Y, et al. Among authors: fradet n. J Biol Chem. 2013 Jan 11;288(2):1184-99. doi: 10.1074/jbc.M112.431825. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184944 Free PMC article.

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo.

Laurin M, Fradet N, Blangy A, Hall A, Vuori K, Côté JF. Laurin M, et al. Among authors: fradet n. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15446-51. doi: 10.1073/pnas.0805546105. Epub 2008 Sep 26. Proc Natl Acad Sci U S A. 2008. PMID: 18820033 Free PMC article.

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