Alfsen A - Search Results

1

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1.

Coutant J, Yu H, Clément MJ, Alfsen A, Toma F, Curmi PA, Bomsel M. Coutant J, et al. Among authors: alfsen a. FASEB J. 2008 Dec;22(12):4338-51. doi: 10.1096/fj.08-113142. Epub 2008 Sep 5. FASEB J. 2008. PMID: 18776068

2

HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide.

Alfsen A, Bomsel M. Alfsen A, et al. J Biol Chem. 2002 Jul 12;277(28):25649-59. doi: 10.1074/jbc.M200554200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940580 Free article.

3

The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent.

Yu H, Alfsen A, Tudor D, Bomsel M. Yu H, et al. Among authors: alfsen a. Cell Calcium. 2008 Jan;43(1):73-82. doi: 10.1016/j.ceca.2007.04.011. Epub 2007 Jun 5. Cell Calcium. 2008. PMID: 17553560

4

Peptide P5 (residues 628-683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection.

Yu H, Tudor D, Alfsen A, Labrosse B, Clavel F, Bomsel M. Yu H, et al. Among authors: alfsen a. Retrovirology. 2008 Oct 16;5:93. doi: 10.1186/1742-4690-5-93. Retrovirology. 2008. PMID: 18925934 Free PMC article.

5

HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer.

Alfsen A, Yu H, Magérus-Chatinet A, Schmitt A, Bomsel M. Alfsen A, et al. Mol Biol Cell. 2005 Sep;16(9):4267-79. doi: 10.1091/mbc.e05-03-0192. Epub 2005 Jun 22. Mol Biol Cell. 2005. PMID: 15975901 Free PMC article.

6

Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.

Matoba N, Griffin TA, Mittman M, Doran JD, Alfsen A, Montefiori DC, Hanson CV, Bomsel M, Mor TS. Matoba N, et al. Among authors: alfsen a. Curr HIV Res. 2008 May;6(3):218-29. doi: 10.2174/157016208784324994. Curr HIV Res. 2008. PMID: 18473785 Free PMC article.

7

Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1.

Alfsen A, Iniguez P, Bouguyon E, Bomsel M. Alfsen A, et al. J Immunol. 2001 May 15;166(10):6257-65. doi: 10.4049/jimmunol.166.10.6257. J Immunol. 2001. PMID: 11342649

8

Entry of viruses through the epithelial barrier: pathogenic trickery.

Bomsel M, Alfsen A. Bomsel M, et al. Among authors: alfsen a. Nat Rev Mol Cell Biol. 2003 Jan;4(1):57-68. doi: 10.1038/nrm1005. Nat Rev Mol Cell Biol. 2003. PMID: 12511869 Free PMC article. Review.

9

Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges.

Bomsel M, Tudor D, Drillet AS, Alfsen A, Ganor Y, Roger MG, Mouz N, Amacker M, Chalifour A, Diomede L, Devillier G, Cong Z, Wei Q, Gao H, Qin C, Yang GB, Zurbriggen R, Lopalco L, Fleury S. Bomsel M, et al. Among authors: alfsen a. Immunity. 2011 Feb 25;34(2):269-80. doi: 10.1016/j.immuni.2011.01.015. Immunity. 2011. PMID: 21315623 Free article.

10

Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649-684), a mucosal subunit HIV/AIDS vaccine candidate.

Matoba N, Geyer BC, Kilbourne J, Alfsen A, Bomsel M, Mor TS. Matoba N, et al. Among authors: alfsen a. Vaccine. 2006 Jun 5;24(23):5047-55. doi: 10.1016/j.vaccine.2006.03.045. Epub 2006 Mar 30. Vaccine. 2006. PMID: 16621185

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