Coop A - Search Results

1

Optimization of labile esters for esterase-assisted accumulation of nitroxides into cells: a model for in vivo EPR imaging.

Burks SR, Ni J, Muralidharan S, Coop A, Kao JP, Rosen GM. Burks SR, et al. Among authors: coop a. Bioconjug Chem. 2008 Oct;19(10):2068-71. doi: 10.1021/bc8001562. Epub 2008 Sep 11. Bioconjug Chem. 2008. PMID: 18783260 Free PMC article.

2

The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans.

Metcalf MD, Aceto MD, Harris LS, Woods JH, Traynor JR, Coop A, May EL. Metcalf MD, et al. Among authors: coop a. Bioorg Med Chem. 2008 Jan 15;16(2):869-73. doi: 10.1016/j.bmc.2007.10.030. Epub 2007 Oct 13. Bioorg Med Chem. 2008. PMID: 17962026 Free PMC article.

3

Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine.

Chen W, Wu H, Bernard D, Metcalf MD, Deschamps JR, Flippen-Anderson JL, MacKerell AD Jr, Coop A. Chen W, et al. Among authors: coop a. J Org Chem. 2003 Mar 7;68(5):1929-32. doi: 10.1021/jo020704m. J Org Chem. 2003. PMID: 12608812

4

Trifluoromethoxyl substituted phenylethylene diamines as high affinity sigma receptor ligands with potent anti-cocaine actions.

Smith TA, Yang X, Wu H, Pouw B, Matsumoto RR, Coop A. Smith TA, et al. Among authors: coop a. J Med Chem. 2008 Jun 12;51(11):3322-5. doi: 10.1021/jm7013666. Epub 2008 May 8. J Med Chem. 2008. PMID: 18461921 Free PMC article.

5

Conformationally sampled pharmacophore for peptidic delta opioid ligands.

Bernard D, Coop A, MacKerell AD Jr. Bernard D, et al. Among authors: coop a. J Med Chem. 2005 Dec 1;48(24):7773-80. doi: 10.1021/jm050785p. J Med Chem. 2005. PMID: 16302816

6

Opioids and efflux transporters. Part 2: P-glycoprotein substrate activity of 3- and 6-substituted morphine analogs.

Cunningham CW, Mercer SL, Hassan HE, Traynor JR, Eddington ND, Coop A. Cunningham CW, et al. Among authors: coop a. J Med Chem. 2008 Apr 10;51(7):2316-20. doi: 10.1021/jm701457j. Epub 2008 Feb 27. J Med Chem. 2008. PMID: 18311899 Free PMC article.

7

The effect of the pyridyl nitrogen position in pyridylpiperazine sigma ligands.

Stavitskaya L, Seminerio MJ, Matthews-Tsourounis MM, Matsumoto RR, Coop A. Stavitskaya L, et al. Among authors: coop a. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2564-5. doi: 10.1016/j.bmcl.2010.02.087. Epub 2010 Mar 1. Bioorg Med Chem Lett. 2010. PMID: 20338757 Free PMC article.

8

Consensus 3D model of μ-opioid receptor ligand efficacy based on a quantitative Conformationally Sampled Pharmacophore.

Shim J, Coop A, MacKerell AD Jr. Shim J, et al. Among authors: coop a. J Phys Chem B. 2011 Jun 9;115(22):7487-96. doi: 10.1021/jp202542g. Epub 2011 May 12. J Phys Chem B. 2011. PMID: 21563754 Free PMC article.

9

Molecular details of the activation of the μ opioid receptor.

Shim J, Coop A, MacKerell AD Jr. Shim J, et al. Among authors: coop a. J Phys Chem B. 2013 Jul 3;117(26):7907-17. doi: 10.1021/jp404238n. Epub 2013 Jun 24. J Phys Chem B. 2013. PMID: 23758404 Free PMC article.

10

Conformational Heterogeneity of Intracellular Loop 3 of the μ-opioid G-protein Coupled Receptor.

Huang J, Lakkaraju SK, Coop A, MacKerell AD Jr. Huang J, et al. Among authors: coop a. J Phys Chem B. 2016 Nov 23;120(46):11897-11904. doi: 10.1021/acs.jpcb.6b09351. Epub 2016 Nov 15. J Phys Chem B. 2016. PMID: 27801588 Free PMC article.

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