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210 results

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Page 1
A new genetic lesion in B-CLL: a NOTCH1 PEST domain mutation.
Di Ianni M, Baldoni S, Rosati E, Ciurnelli R, Cavalli L, Martelli MF, Marconi P, Screpanti I, Falzetti F. Di Ianni M, et al. Among authors: screpanti i. Br J Haematol. 2009 Sep;146(6):689-91. doi: 10.1111/j.1365-2141.2009.07816.x. Epub 2009 Jul 10. Br J Haematol. 2009. PMID: 19604236 Free article. No abstract available.
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.
Rosati E, Sabatini R, Rampino G, De Falco F, Di Ianni M, Falzetti F, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: screpanti i. Blood. 2010 Oct 14;116(15):2713-23. doi: 10.1182/blood-2010-03-275628. Epub 2010 Jul 13. Blood. 2010. PMID: 20628148 Free article.
NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL.
Sportoletti P, Baldoni S, Cavalli L, Del Papa B, Bonifacio E, Ciurnelli R, Bell AS, Di Tommaso A, Rosati E, Crescenzi B, Mecucci C, Screpanti I, Marconi P, Martelli MF, Di Ianni M, Falzetti F. Sportoletti P, et al. Among authors: screpanti i. Br J Haematol. 2010 Nov;151(4):404-6. doi: 10.1111/j.1365-2141.2010.08368.x. Epub 2010 Aug 31. Br J Haematol. 2010. PMID: 20813007 Free article. No abstract available.
γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation.
Rosati E, Sabatini R, De Falco F, Del Papa B, Falzetti F, Di Ianni M, Cavalli L, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: screpanti i. Int J Cancer. 2013 Apr 15;132(8):1940-53. doi: 10.1002/ijc.27863. Epub 2012 Oct 17. Int J Cancer. 2013. PMID: 23001755
NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells.
Di Ianni M, Baldoni S, Del Papa B, Aureli P, Dorillo E, De Falco F, Albi E, Varasano E, Di Tommaso A, Giancola R, Accorsi P, Rotta G, Rompietti C, Silva Barcelos EC, Campese AF, Di Bartolomeo P, Screpanti I, Rosati E, Falzetti F, Sportoletti P. Di Ianni M, et al. Among authors: screpanti i. Front Oncol. 2018 Apr 20;8:105. doi: 10.3389/fonc.2018.00105. eCollection 2018. Front Oncol. 2018. PMID: 29732315 Free PMC article.
IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation.
De Falco F, Del Papa B, Baldoni S, Sabatini R, Falzetti F, Di Ianni M, Martelli MP, Mezzasoma F, Pelullo M, Marconi P, Sportoletti P, Screpanti I, Rosati E. De Falco F, et al. Among authors: screpanti i. Cell Death Dis. 2018 Nov 26;9(12):1160. doi: 10.1038/s41419-018-1185-6. Cell Death Dis. 2018. PMID: 30478302 Free PMC article.
GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL.
De Falco F, Rompietti C, Sorcini D, Esposito A, Scialdone A, Baldoni S, Del Papa B, Adamo FM, Silva Barcelos EC, Dorillo E, Stella A, Di Ianni M, Screpanti I, Sportoletti P, Rosati E. De Falco F, et al. Among authors: screpanti i. Cell Death Dis. 2022 Sep 1;13(9):755. doi: 10.1038/s41419-022-05178-w. Cell Death Dis. 2022. PMID: 36050315 Free PMC article.
210 results