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Page 1
'Reverse' alpha-ketoamide-based p38 MAP kinase inhibitors.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: ceide sc. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5456-9. doi: 10.1016/j.bmcl.2008.09.028. Epub 2008 Sep 11. Bioorg Med Chem Lett. 2008. PMID: 18835164
The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: ceide sc. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1772-7. doi: 10.1016/j.bmcl.2008.02.033. Epub 2008 Feb 16. Bioorg Med Chem Lett. 2008. PMID: 18325768
KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: ceide sc. Eur J Pharmacol. 2010 Apr 25;632(1-3):93-102. doi: 10.1016/j.ejphar.2010.01.011. Epub 2010 Feb 2. Eur J Pharmacol. 2010. PMID: 20132813
Optimization of alpha-ketoamide based p38 inhibitors through modifications to the region that binds to the allosteric site.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Kucharski J, Lum C, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Urban J, Wang Z, Larson CJ. Montalban AG, et al. Among authors: ceide sc. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4819-24. doi: 10.1016/j.bmcl.2010.06.102. Bioorg Med Chem Lett. 2010. PMID: 20663667
Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests.
Bartfai T, Lu X, Badie-Mahdavi H, Barr AM, Mazarati A, Hua XY, Yaksh T, Haberhauer G, Ceide SC, Trembleau L, Somogyi L, Kröck L, Rebek J Jr. Bartfai T, et al. Among authors: ceide sc. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. doi: 10.1073/pnas.0403802101. Epub 2004 Jul 6. Proc Natl Acad Sci U S A. 2004. PMID: 15240875 Free PMC article.
Synthesis of galmic: a nonpeptide galanin receptor agonist.
Ceide SC, Trembleau L, Haberhauer G, Somogyi L, Lu X, Bartfai T, Rebek J Jr. Ceide SC, et al. Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16727-32. doi: 10.1073/pnas.0407543101. Epub 2004 Nov 19. Proc Natl Acad Sci U S A. 2004. PMID: 15557002 Free PMC article.