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Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture.
Allen JS, Pang K, Skowera A, Ellis R, Rackham C, Lozanoska-Ochser B, Tree T, Leslie RD, Tremble JM, Dayan CM, Peakman M. Allen JS, et al. Among authors: rackham c. Diabetes. 2009 Jan;58(1):138-45. doi: 10.2337/db08-0964. Epub 2008 Oct 3. Diabetes. 2009. PMID: 18835928 Free PMC article.
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.
Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Drijfhout JW, Ossendorp F, Roep BO, Peakman M. Skowera A, et al. Among authors: rackham c. J Clin Invest. 2008 Oct;118(10):3390-402. doi: 10.1172/JCI35449. J Clin Invest. 2008. PMID: 18802479 Free PMC article.
Assessing Islet Transplantation Outcome in Mice.
King AJF, Rackham CL. King AJF, et al. Among authors: rackham cl. Methods Mol Biol. 2020;2076:265-280. doi: 10.1007/978-1-4939-9882-1_16. Methods Mol Biol. 2020. PMID: 31586334
22 results