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Page 1
STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.
Lu SX, Alpdogan O, Lin J, Balderas R, Campos-Gonzalez R, Wang X, Gao GJ, Suh D, King C, Chow M, Smith OM, Hubbard VM, Bautista JL, Cabrera-Perez J, Zakrzewski JL, Kochman AA, Chow A, Altan-Bonnet G, van den Brink MR. Lu SX, et al. Among authors: hubbard vm. Blood. 2008 Dec 15;112(13):5254-8. doi: 10.1182/blood-2008-03-147322. Epub 2008 Oct 6. Blood. 2008. PMID: 18838616 Free PMC article.
GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease.
Muriglan SJ, Ramirez-Montagut T, Alpdogan O, Van Huystee TW, Eng JM, Hubbard VM, Kochman AA, Tjoe KH, Riccardi C, Pandolfi PP, Sakaguchi S, Houghton AN, Van Den Brink MR. Muriglan SJ, et al. Among authors: hubbard vm. J Exp Med. 2004 Jul 19;200(2):149-57. doi: 10.1084/jem.20040116. Epub 2004 Jul 12. J Exp Med. 2004. PMID: 15249593 Free PMC article.
CCR2 is required for CD8-induced graft-versus-host disease.
Terwey TH, Kim TD, Kochman AA, Hubbard VM, Lu S, Zakrzewski JL, Ramirez-Montagut T, Eng JM, Muriglan SJ, Heller G, Murphy GF, Liu C, Budak-Alpdogan T, Alpdogan O, van den Brink MR. Terwey TH, et al. Among authors: hubbard vm. Blood. 2005 Nov 1;106(9):3322-30. doi: 10.1182/blood-2005-05-1860. Epub 2005 Jul 21. Blood. 2005. PMID: 16037386 Free PMC article.
Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration.
Alpdogan O, Hubbard VM, Smith OM, Patel N, Lu S, Goldberg GL, Gray DH, Feinman J, Kochman AA, Eng JM, Suh D, Muriglan SJ, Boyd RL, van den Brink MR. Alpdogan O, et al. Among authors: hubbard vm. Blood. 2006 Mar 15;107(6):2453-60. doi: 10.1182/blood-2005-07-2831. Epub 2005 Nov 22. Blood. 2006. PMID: 16304055 Free PMC article.
Rapidly proliferating CD44hi peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation.
Alpdogan SO, Lu SX, Patel N, McGoldrick S, Suh D, Budak-Alpdogan T, Smith OM, Grubin J, King C, Goldberg GL, Hubbard VM, Kochman AA, van den Brink MR. Alpdogan SO, et al. Among authors: hubbard vm. Blood. 2008 Dec 1;112(12):4755-64. doi: 10.1182/blood-2008-02-142737. Epub 2008 Sep 24. Blood. 2008. PMID: 18815289 Free PMC article.
Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
Lu SX, Holland AM, Na IK, Terwey TH, Alpdogan O, Bautista JL, Smith OM, Suh D, King C, Kochman A, Hubbard VM, Rao UK, Yim N, Liu C, Laga AC, Murphy G, Jenq RR, Zakrzewski JL, Penack O, Dykstra L, Bampoe K, Perez L, Furie B, Furie B, van den Brink MR. Lu SX, et al. Among authors: hubbard vm. J Immunol. 2010 Aug 1;185(3):1912-9. doi: 10.4049/jimmunol.0903148. Epub 2010 Jul 9. J Immunol. 2010. PMID: 20622117 Free PMC article.
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