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Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects.
Luo X, Chen J, Song WX, Tang N, Luo J, Deng ZL, Sharff KA, He G, Bi Y, He BC, Bennett E, Huang J, Kang Q, Jiang W, Su Y, Zhu GH, Yin H, He Y, Wang Y, Souris JS, Chen L, Zuo GW, Montag AG, Reid RR, Haydon RC, Luu HH, He TC. Luo X, et al. Among authors: chen j, chen l. Lab Invest. 2008 Dec;88(12):1264-77. doi: 10.1038/labinvest.2008.98. Epub 2008 Oct 6. Lab Invest. 2008. PMID: 18838962 Free PMC article.
Wnt signaling and human diseases: what are the therapeutic implications?
Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, Tang N, Haydon RC, Luu HH, He TC. Luo J, et al. Among authors: chen j. Lab Invest. 2007 Feb;87(2):97-103. doi: 10.1038/labinvest.3700509. Epub 2007 Jan 8. Lab Invest. 2007. PMID: 17211410 Free article. Review.
Regulation of osteogenic differentiation during skeletal development.
Deng ZL, Sharff KA, Tang N, Song WX, Luo J, Luo X, Chen J, Bennett E, Reid R, Manning D, Xue A, Montag AG, Luu HH, Haydon RC, He TC. Deng ZL, et al. Among authors: chen j. Front Biosci. 2008 Jan 1;13:2001-21. doi: 10.2741/2819. Front Biosci. 2008. PMID: 17981687 Review.
S100A6 expression and function in human osteosarcoma.
Luo X, Sharff KA, Chen J, He TC, Luu HH. Luo X, et al. Among authors: chen j. Clin Orthop Relat Res. 2008 Sep;466(9):2060-70. doi: 10.1007/s11999-008-0361-x. Epub 2008 Jul 9. Clin Orthop Relat Res. 2008. PMID: 18612712 Free PMC article.
A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells.
Kang Q, Song WX, Luo Q, Tang N, Luo J, Luo X, Chen J, Bi Y, He BC, Park JK, Jiang W, Tang Y, Huang J, Su Y, Zhu GH, He Y, Yin H, Hu Z, Wang Y, Chen L, Zuo GW, Pan X, Shen J, Vokes T, Reid RR, Haydon RC, Luu HH, He TC. Kang Q, et al. Among authors: chen j, chen l. Stem Cells Dev. 2009 May;18(4):545-59. doi: 10.1089/scd.2008.0130. Stem Cells Dev. 2009. PMID: 18616389 Free PMC article.
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
Sharff KA, Song WX, Luo X, Tang N, Luo J, Chen J, Bi Y, He BC, Huang J, Li X, Jiang W, Zhu GH, Su Y, He Y, Shen J, Wang Y, Chen L, Zuo GW, Liu B, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Sharff KA, et al. Among authors: chen j, chen l. J Biol Chem. 2009 Jan 2;284(1):649-659. doi: 10.1074/jbc.M806389200. Epub 2008 Nov 5. J Biol Chem. 2009. PMID: 18986983 Free PMC article.
BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling.
Tang N, Song WX, Luo J, Luo X, Chen J, Sharff KA, Bi Y, He BC, Huang JY, Zhu GH, Su YX, Jiang W, Tang M, He Y, Wang Y, Chen L, Zuo GW, Shen J, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Tang N, et al. Among authors: chen j, chen l. J Cell Mol Med. 2009 Aug;13(8B):2448-2464. doi: 10.1111/j.1582-4934.2008.00569.x. Epub 2008 Nov 3. J Cell Mol Med. 2009. PMID: 19175684 Free PMC article.
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