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Page 1
Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
Tremblay MR, Nevalainen M, Nair SJ, Porter JR, Castro AC, Behnke ML, Yu LC, Hagel M, White K, Faia K, Grenier L, Campbell MJ, Cushing J, Woodward CN, Hoyt J, Foley MA, Read MA, Sydor JR, Tong JK, Palombella VJ, McGovern K, Adams J. Tremblay MR, et al. Among authors: yu lc. J Med Chem. 2008 Nov 13;51(21):6646-9. doi: 10.1021/jm8008508. Epub 2008 Oct 9. J Med Chem. 2008. PMID: 18842035
Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
Tremblay MR, Lescarbeau A, Grogan MJ, Tan E, Lin G, Austad BC, Yu LC, Behnke ML, Nair SJ, Hagel M, White K, Conley J, Manna JD, Alvarez-Diez TM, Hoyt J, Woodward CN, Sydor JR, Pink M, MacDougall J, Campbell MJ, Cushing J, Ferguson J, Curtis MS, McGovern K, Read MA, Palombella VJ, Adams J, Castro AC. Tremblay MR, et al. Among authors: yu lc. J Med Chem. 2009 Jul 23;52(14):4400-18. doi: 10.1021/jm900305z. J Med Chem. 2009. PMID: 19522463
Hematopoietic Cell Transplant compared with Standard Care in Adolescents and Young Adults with Sickle Cell Disease.
Walters MC, Eapen M, Liu Y, El Rassi F, Waller EK, Levine JE, Strouse JJ, Antin JH, Parikh SH, Bakshi N, Dampier CD, Jaroscak JJ, Bergmann S, Wong TE, Kota VK, Pace BS, Lekakis LJ, Lulla PD, Nickel R, Kasow KA, Popat UR, Smith WR, Yu LC, DiFronzo NL, Geller NL, Kamani N, Klings ES, Hassell K, Mendizabal AM, Sullivan K, Neuberg DS, Krishnamurti L. Walters MC, et al. Among authors: yu lc. Blood Adv. 2024 Oct 29:bloodadvances.2024013926. doi: 10.1182/bloodadvances.2024013926. Online ahead of print. Blood Adv. 2024. PMID: 39471440
457 results