Ronai Z - Search Results

1

Inhibition of Siah ubiquitin ligase function.

Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Möller A, et al. Among authors: ronai z. Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13. Oncogene. 2009. PMID: 18850011 Free PMC article.

2

Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability.

Kim H, Claps G, Möller A, Bowtell D, Lu X, Ronai ZA. Kim H, et al. Among authors: ronai za. Oncogene. 2014 Apr 10;33(15):2004-10. doi: 10.1038/onc.2013.149. Epub 2013 May 6. Oncogene. 2014. PMID: 23644657 Free PMC article.

3

Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.

Wong CS, Sceneay J, House CM, Halse HM, Liu MC, George J, Hunnam TC, Parker BS, Haviv I, Ronai Z, Cullinane C, Bowtell DD, Möller A. Wong CS, et al. Among authors: ronai z. Cancer Res. 2012 Apr 1;72(7):1694-704. doi: 10.1158/0008-5472.CAN-11-3310. Epub 2012 Feb 21. Cancer Res. 2012. PMID: 22354750

4

Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.

Habelhah H, Laine A, Erdjument-Bromage H, Tempst P, Gershwin ME, Bowtell DD, Ronai Z. Habelhah H, et al. Among authors: ronai z. J Biol Chem. 2004 Dec 17;279(51):53782-8. doi: 10.1074/jbc.M410315200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15466852 Free article.

5

The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.

Qi J, Nakayama K, Gaitonde S, Goydos JS, Krajewski S, Eroshkin A, Bar-Sagi D, Bowtell D, Ronai Z. Qi J, et al. Among authors: ronai z. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16713-8. doi: 10.1073/pnas.0804063105. Epub 2008 Oct 22. Proc Natl Acad Sci U S A. 2008. PMID: 18946040 Free PMC article.

6

The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity.

Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA. Qi J, et al. Cancer Cell. 2013 Mar 18;23(3):332-46. doi: 10.1016/j.ccr.2013.02.016. Cancer Cell. 2013. PMID: 23518348 Free PMC article.

7

Fine tuning of the UPR by the ubiquitin ligases Siah1/2.

Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. Scortegagna M, et al. PLoS Genet. 2014 May 8;10(5):e1004348. doi: 10.1371/journal.pgen.1004348. eCollection 2014 May. PLoS Genet. 2014. PMID: 24809345 Free PMC article.

8

Stress-induced decrease in TRAF2 stability is mediated by Siah2.

Habelhah H, Frew IJ, Laine A, Janes PW, Relaix F, Sassoon D, Bowtell DD, Ronai Z. Habelhah H, et al. Among authors: ronai z. EMBO J. 2002 Nov 1;21(21):5756-65. doi: 10.1093/emboj/cdf576. EMBO J. 2002. PMID: 12411493 Free PMC article.

9

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.

Qi J, Nakayama K, Cardiff RD, Borowsky AD, Kaul K, Williams R, Krajewski S, Mercola D, Carpenter PM, Bowtell D, Ronai ZA. Qi J, et al. Cancer Cell. 2010 Jul 13;18(1):23-38. doi: 10.1016/j.ccr.2010.05.024. Cancer Cell. 2010. PMID: 20609350 Free PMC article.

10

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.

Nakayama K, Frew IJ, Hagensen M, Skals M, Habelhah H, Bhoumik A, Kadoya T, Erdjument-Bromage H, Tempst P, Frappell PB, Bowtell DD, Ronai Z. Nakayama K, et al. Among authors: ronai z. Cell. 2004 Jun 25;117(7):941-52. doi: 10.1016/j.cell.2004.06.001. Cell. 2004. PMID: 15210114 Free article.

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