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Inhibition of Siah ubiquitin ligase function.
Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Möller A, et al. Among authors: wong cs. Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13. Oncogene. 2009. PMID: 18850011 Free PMC article.
The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.
Chan P, Möller A, Liu MC, Sceneay JE, Wong CS, Waddell N, Huang KT, Dobrovic A, Millar EK, O'Toole SA, McNeil CM, Sutherland RL, Bowtell DD, Fox SB. Chan P, et al. Among authors: wong cs. Breast Cancer Res. 2011 Feb 9;13(1):R19. doi: 10.1186/bcr2828. Breast Cancer Res. 2011. PMID: 21306611 Free PMC article.
Siah: a promising anticancer target.
Wong CS, Möller A. Wong CS, et al. Cancer Res. 2013 Apr 15;73(8):2400-6. doi: 10.1158/0008-5472.CAN-12-4348. Epub 2013 Mar 1. Cancer Res. 2013. PMID: 23455005 Review.
Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer.
Rautela J, Baschuk N, Slaney CY, Jayatilleke KM, Xiao K, Bidwell BN, Lucas EC, Hawkins ED, Lock P, Wong CS, Chen W, Anderson RL, Hertzog PJ, Andrews DM, Möller A, Parker BS. Rautela J, et al. Among authors: wong cs. Cancer Immunol Res. 2015 Nov;3(11):1207-17. doi: 10.1158/2326-6066.CIR-15-0065. Epub 2015 Jul 21. Cancer Immunol Res. 2015. PMID: 26198985
Siah2-deficient mice show impaired skin wound repair.
Musyoka JN, Liu MC, Pouniotis DS, Wong CS, Bowtell DD, Little PJ, Getachew R, Möller A, Darby IA. Musyoka JN, et al. Among authors: wong cs. Wound Repair Regen. 2013 May-Jun;21(3):437-47. doi: 10.1111/wrr.12045. Epub 2013 Apr 29. Wound Repair Regen. 2013. PMID: 23627548
1,145 results