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Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.
Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR. Yvan-Charvet L, et al. Among authors: pagler ta. Circulation. 2008 Oct 28;118(18):1837-47. doi: 10.1161/CIRCULATIONAHA.108.793869. Epub 2008 Oct 13. Circulation. 2008. PMID: 18852364 Free PMC article.
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR. Westerterp M, et al. Among authors: pagler ta. Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9. Circ Res. 2013. PMID: 23572498 Free PMC article.
16 results