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The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone(mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, balb/ca mice or C57bl/6J-min mice.
Steffensen IL, Paulsen JE, Engeset D, Kronberg L, Alexander J. Steffensen IL, et al. Pharmacol Toxicol. 1999 Aug;85(2):56-64. doi: 10.1111/j.1600-0773.1999.tb00067.x. Pharmacol Toxicol. 1999. PMID: 10488686
DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).
Steffensen IL, Fretland AJ, Paulsen JE, Feng Y, Eide TJ, Devanaboyina US, Hein DW, Alexander J. Steffensen IL, et al. Pharmacol Toxicol. 2000 Jun;86(6):257-63. doi: 10.1111/j.0901-9928.2000.860603.x. Pharmacol Toxicol. 2000. PMID: 10895988
539 results