Cichewicz RH - Search Results

1

Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges.

Amagata T, Johnson TA, Cichewicz RH, Tenney K, Mooberry SL, Media J, Edelstein M, Valeriote FA, Crews P. Amagata T, et al. Among authors: cichewicz rh. J Med Chem. 2008 Nov 27;51(22):7234-42. doi: 10.1021/jm8008585. J Med Chem. 2008. PMID: 18942825 Free PMC article.

2

Identification of Fungus-Derived Natural Products as New Antigiardial Scaffolds.

Hulverson MA, Michaels SA, Lee JW, Wendt KL, Tran LT, Choi R, Van Voorhis WC, Cichewicz RH, Ojo KK. Hulverson MA, et al. Among authors: cichewicz rh. Microbiol Spectr. 2023 Jun 15;11(3):e0064723. doi: 10.1128/spectrum.00647-23. Epub 2023 Apr 11. Microbiol Spectr. 2023. PMID: 37039683 Free PMC article.

3

In Vitro Susceptibility and Resistance of Mycoplasma genitalium to Nitroimidazoles.

Wood GE, Kim CM, Aguila LKT, Cichewicz RH. Wood GE, et al. Among authors: cichewicz rh. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0000623. doi: 10.1128/aac.00006-23. Epub 2023 Mar 9. Antimicrob Agents Chemother. 2023. PMID: 37070857 Free PMC article.

4

Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family.

Cichewicz RH, Valeriote FA, Crews P. Cichewicz RH, et al. Org Lett. 2004 Jun 10;6(12):1951-4. doi: 10.1021/ol049503q. Org Lett. 2004. PMID: 15176791

5

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Segraves EN, et al. Among authors: cichewicz rh. J Med Chem. 2004 Jul 29;47(16):4060-5. doi: 10.1021/jm049872s. J Med Chem. 2004. PMID: 15267244

6

Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Cichewicz RH, et al. J Am Chem Soc. 2004 Nov 17;126(45):14910-20. doi: 10.1021/ja046082z. J Am Chem Soc. 2004. PMID: 15535718

7

Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis.

Cichewicz RH, Clifford LJ, Lassen PR, Cao X, Freedman TB, Nafie LA, Deschamps JD, Kenyon VA, Flanary JR, Holman TR, Crews P. Cichewicz RH, et al. Bioorg Med Chem. 2005 Oct 1;13(19):5600-12. doi: 10.1016/j.bmc.2005.06.020. Bioorg Med Chem. 2005. PMID: 16039133

8

Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

Johnson TA, Tenney K, Cichewicz RH, Morinaka BI, White KN, Amagata T, Subramanian B, Media J, Mooberry SL, Valeriote FA, Crews P. Johnson TA, et al. Among authors: cichewicz rh. J Med Chem. 2007 Aug 9;50(16):3795-803. doi: 10.1021/jm070410z. Epub 2007 Jul 10. J Med Chem. 2007. PMID: 17622130 Free PMC article.

9

Reassessing the ichthyotoxin profile of cultured Prymnesium parvum (golden algae) and comparing it to samples collected from recent freshwater bloom and fish kill events in North America.

Henrikson JC, Gharfeh MS, Easton AC, Easton JD, Glenn KL, Shadfan M, Mooberry SL, Hambright KD, Cichewicz RH. Henrikson JC, et al. Among authors: cichewicz rh. Toxicon. 2010 Jun 15;55(7):1396-404. doi: 10.1016/j.toxicon.2010.02.017. Epub 2010 Feb 23. Toxicon. 2010. PMID: 20184911

10

Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity.

Du L, Robles AJ, King JB, Powell DR, Miller AN, Mooberry SL, Cichewicz RH. Du L, et al. Among authors: cichewicz rh. Angew Chem Int Ed Engl. 2014 Jan 13;53(3):804-9. doi: 10.1002/anie.201306549. Epub 2013 Nov 27. Angew Chem Int Ed Engl. 2014. PMID: 24285637 Free PMC article.

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