Winkler A - Search Results

1

A concerted mechanism for berberine bridge enzyme.

Winkler A, Lyskowski A, Riedl S, Puhl M, Kutchan TM, Macheroux P, Gruber K. Winkler A, et al. Nat Chem Biol. 2008 Dec;4(12):739-41. doi: 10.1038/nchembio.123. Epub 2008 Oct 26. Nat Chem Biol. 2008. PMID: 18953357 Free article.

2

Biochemical evidence that berberine bridge enzyme belongs to a novel family of flavoproteins containing a bi-covalently attached FAD cofactor.

Winkler A, Hartner F, Kutchan TM, Glieder A, Macheroux P. Winkler A, et al. J Biol Chem. 2006 Jul 28;281(30):21276-21285. doi: 10.1074/jbc.M603267200. Epub 2006 May 25. J Biol Chem. 2006. PMID: 16728404 Free article.

3

6-S-cysteinylation of bi-covalently attached FAD in berberine bridge enzyme tunes the redox potential for optimal activity.

Winkler A, Kutchan TM, Macheroux P. Winkler A, et al. J Biol Chem. 2007 Aug 17;282(33):24437-43. doi: 10.1074/jbc.M703642200. Epub 2007 Jun 15. J Biol Chem. 2007. PMID: 17573342 Free article.

4

Functional roles of the 6-S-cysteinyl, 8alpha-N1-histidyl FAD in glucooligosaccharide oxidase from Acremonium strictum.

Huang CH, Winkler A, Chen CL, Lai WL, Tsai YC, Macheroux P, Liaw SH. Huang CH, et al. Among authors: winkler a. J Biol Chem. 2008 Nov 7;283(45):30990-6. doi: 10.1074/jbc.M804331200. Epub 2008 Sep 3. J Biol Chem. 2008. PMID: 18768475 Free PMC article.

5

Structural and mechanistic studies reveal the functional role of bicovalent flavinylation in berberine bridge enzyme.

Winkler A, Motz K, Riedl S, Puhl M, Macheroux P, Gruber K. Winkler A, et al. J Biol Chem. 2009 Jul 24;284(30):19993-20001. doi: 10.1074/jbc.M109.015727. Epub 2009 May 19. J Biol Chem. 2009. PMID: 19457868 Free PMC article.

6

Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine.

Winkler A, Puhl M, Weber H, Kutchan TM, Gruber K, Macheroux P. Winkler A, et al. Phytochemistry. 2009 Jun;70(9):1092-1097. doi: 10.1016/j.phytochem.2009.06.005. Epub 2009 Jun 29. Phytochemistry. 2009. PMID: 19570558

7

Biocatalytic enantioselective oxidative C-C coupling by aerobic C-H activation.

Schrittwieser JH, Resch V, Sattler JH, Lienhart WD, Durchschein K, Winkler A, Gruber K, Macheroux P, Kroutil W. Schrittwieser JH, et al. Among authors: winkler a. Angew Chem Int Ed Engl. 2011 Feb 1;50(5):1068-71. doi: 10.1002/anie.201006268. Epub 2011 Jan 18. Angew Chem Int Ed Engl. 2011. PMID: 21268196 No abstract available.

8

Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme.

Wallner S, Winkler A, Riedl S, Dully C, Horvath S, Gruber K, Macheroux P. Wallner S, et al. Among authors: winkler a. Biochemistry. 2012 Aug 7;51(31):6139-47. doi: 10.1021/bi300411n. Epub 2012 Jul 25. Biochemistry. 2012. PMID: 22757961 Free PMC article.

9

Structural and biochemical properties of LuxF from Photobacterium leiognathi.

Bergner T, Tabib CR, Winkler A, Stipsits S, Kayer H, Lee J, Malthouse JP, Mayhew S, Müller F, Gruber K, Macheroux P. Bergner T, et al. Among authors: winkler a. Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1466-75. doi: 10.1016/j.bbapap.2015.07.008. Epub 2015 Jul 21. Biochim Biophys Acta. 2015. PMID: 26209460

10

The family of berberine bridge enzyme-like enzymes: A treasure-trove of oxidative reactions.

Daniel B, Konrad B, Toplak M, Lahham M, Messenlehner J, Winkler A, Macheroux P. Daniel B, et al. Among authors: winkler a. Arch Biochem Biophys. 2017 Oct 15;632:88-103. doi: 10.1016/j.abb.2017.06.023. Epub 2017 Jul 1. Arch Biochem Biophys. 2017. PMID: 28676375 Free article. Review.

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