Markham GD - Search Results

1

Structure-function relationships in methionine adenosyltransferases.

Markham GD, Pajares MA. Markham GD, et al. Cell Mol Life Sci. 2009 Feb;66(4):636-48. doi: 10.1007/s00018-008-8516-1. Cell Mol Life Sci. 2009. PMID: 18953685 Free PMC article. Review.

2

Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases.

Garrido F, Alfonso C, Taylor JC, Markham GD, Pajares MA. Garrido F, et al. Among authors: markham gd. Biochim Biophys Acta. 2009 Jul;1794(7):1082-90. doi: 10.1016/j.bbapap.2009.03.018. Epub 2009 Apr 5. Biochim Biophys Acta. 2009. PMID: 19348969 Free PMC article.

3

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride.

Garrido F, Taylor JC, Alfonso C, Markham GD, Pajares MA. Garrido F, et al. Among authors: markham gd. Amino Acids. 2012 Jan;42(1):361-73. doi: 10.1007/s00726-010-0813-y. Epub 2010 Dec 4. Amino Acids. 2012. PMID: 21132339 Free PMC article.

4

Methionine adenosyltransferase (s-adenosylmethionine synthetase).

Pajares MA, Markham GD. Pajares MA, et al. Among authors: markham gd. Adv Enzymol Relat Areas Mol Biol. 2011;78:449-521. doi: 10.1002/9781118105771.ch11. Adv Enzymol Relat Areas Mol Biol. 2011. PMID: 22220481 Review. No abstract available.

5

Discovery of novel types of inhibitors of S-adenosylmethionine synthesis by virtual screening.

Taylor JC, Bock CW, Takusagawa F, Markham GD. Taylor JC, et al. Among authors: markham gd. J Med Chem. 2009 Oct 8;52(19):5967-73. doi: 10.1021/jm9006142. J Med Chem. 2009. PMID: 19739644 Free PMC article.

6

The bifunctional active site of S-adenosylmethionine synthetase. Roles of the basic residues.

Taylor JC, Markham GD. Taylor JC, et al. Among authors: markham gd. J Biol Chem. 2000 Feb 11;275(6):4060-5. doi: 10.1074/jbc.275.6.4060. J Biol Chem. 2000. PMID: 10660564 Free article.

7

The active site loop of S-adenosylmethionine synthetase modulates catalytic efficiency.

Taylor JC, Takusagawa F, Markham GD. Taylor JC, et al. Among authors: markham gd. Biochemistry. 2002 Jul 30;41(30):9358-69. doi: 10.1021/bi025851t. Biochemistry. 2002. PMID: 12135357

8

Enzymatic properties of S-adenosylmethionine synthetase from the archaeon Methanococcus jannaschii.

Lu ZJ, Markham GD. Lu ZJ, et al. Among authors: markham gd. J Biol Chem. 2002 May 10;277(19):16624-31. doi: 10.1074/jbc.M110456200. Epub 2002 Feb 28. J Biol Chem. 2002. PMID: 11872742 Free article.

9

The conformations of a substrate and a product bound to the active site of S-adenosylmethionine synthetase.

Schalk-Hihi C, Markham GD. Schalk-Hihi C, et al. Among authors: markham gd. Biochemistry. 1999 Feb 23;38(8):2542-50. doi: 10.1021/bi9822933. Biochemistry. 1999. PMID: 10029549

10

The bifunctional active site of s-adenosylmethionine synthetase. Roles of the active site aspartates.

Taylor JC, Markham GD. Taylor JC, et al. Among authors: markham gd. J Biol Chem. 1999 Nov 12;274(46):32909-14. doi: 10.1074/jbc.274.46.32909. J Biol Chem. 1999. PMID: 10551856 Free article.

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