Samudio I - Search Results

1

CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure.

Fiegl M, Samudio I, Clise-Dwyer K, Burks JK, Mnjoyan Z, Andreeff M. Fiegl M, et al. Among authors: samudio i. Blood. 2009 Feb 12;113(7):1504-12. doi: 10.1182/blood-2008-06-161539. Epub 2008 Oct 28. Blood. 2009. PMID: 18957686 Free PMC article.

2

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.

Kojima K, Konopleva M, Samudio IJ, Shikami M, Cabreira-Hansen M, McQueen T, Ruvolo V, Tsao T, Zeng Z, Vassilev LT, Andreeff M. Kojima K, et al. Blood. 2005 Nov 1;106(9):3150-9. doi: 10.1182/blood-2005-02-0553. Epub 2005 Jul 12. Blood. 2005. PMID: 16014563 Free PMC article.

3

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

Zeng Z, Sarbassov dos D, Samudio IJ, Yee KW, Munsell MF, Ellen Jackson C, Giles FJ, Sabatini DM, Andreeff M, Konopleva M. Zeng Z, et al. Blood. 2007 Apr 15;109(8):3509-12. doi: 10.1182/blood-2006-06-030833. Epub 2006 Dec 19. Blood. 2007. PMID: 17179228 Free PMC article.

4

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling X, Frolova O, Levis M, Rubin JB, Negrin RR, Estey EH, Konoplev S, Andreeff M, Konopleva M. Zeng Z, et al. Blood. 2009 Jun 11;113(24):6215-24. doi: 10.1182/blood-2008-05-158311. Epub 2008 Oct 27. Blood. 2009. PMID: 18955566 Free PMC article.

5

Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.

Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N Jr, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M. Zeng Z, et al. Cancer Res. 2006 Apr 1;66(7):3737-46. doi: 10.1158/0008-5472.CAN-05-1278. Cancer Res. 2006. PMID: 16585200

6

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

Zeng Z, Samudio IJ, Munsell M, An J, Huang Z, Estey E, Andreeff M, Konopleva M. Zeng Z, et al. Mol Cancer Ther. 2006 Dec;5(12):3113-21. doi: 10.1158/1535-7163.MCT-06-0228. Mol Cancer Ther. 2006. PMID: 17172414

7

Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.

Kojima K, Konopleva M, Samudio IJ, Ruvolo V, Andreeff M. Kojima K, et al. Cancer Res. 2007 Apr 1;67(7):3210-9. doi: 10.1158/0008-5472.CAN-06-2712. Cancer Res. 2007. PMID: 17409429

8

Activation of p53 signaling by MI-63 induces apoptosis in acute myeloid leukemia cells.

Samudio IJ, Duvvuri S, Clise-Dwyer K, Watt JC, Mak D, Kantarjian H, Yang D, Ruvolo V, Borthakur G. Samudio IJ, et al. Leuk Lymphoma. 2010 May;51(5):911-919. doi: 10.3109/10428191003731325. Leuk Lymphoma. 2010. PMID: 20423286 Free PMC article.

9

Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure.

Samudio I, Konopleva M, Safe S, McQueen T, Andreeff M. Samudio I, et al. Mol Cancer Ther. 2005 Dec;4(12):1982-92. doi: 10.1158/1535-7163.MCT-05-0247. Mol Cancer Ther. 2005. PMID: 16373713

10

The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.

Samudio I, Fiegl M, McQueen T, Clise-Dwyer K, Andreeff M. Samudio I, et al. Cancer Res. 2008 Jul 1;68(13):5198-205. doi: 10.1158/0008-5472.CAN-08-0555. Cancer Res. 2008. PMID: 18593920 Free PMC article.

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