Flevaris P - Search Results

1

Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway.

Flevaris P, Li Z, Zhang G, Zheng Y, Liu J, Du X. Flevaris P, et al. Blood. 2009 Jan 22;113(4):893-901. doi: 10.1182/blood-2008-05-155978. Epub 2008 Oct 28. Blood. 2009. PMID: 18957688 Free PMC article.

2

RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.

Su X, Mi J, Yan J, Flevaris P, Lu Y, Liu H, Ruan Z, Wang X, Kieffer N, Chen S, Du X, Xi X. Su X, et al. Among authors: flevaris p. Blood. 2008 Aug 1;112(3):592-602. doi: 10.1182/blood-2007-09-110437. Epub 2008 Apr 8. Blood. 2008. PMID: 18398066 Free PMC article.

3

G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling.

Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X. Gong H, et al. Among authors: flevaris p. Science. 2010 Jan 15;327(5963):340-3. doi: 10.1126/science.1174779. Science. 2010. PMID: 20075254 Free PMC article.

4

Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain.

Xi X, Flevaris P, Stojanovic A, Chishti A, Phillips DR, Lam SC, Du X. Xi X, et al. Among authors: flevaris p. J Biol Chem. 2006 Oct 6;281(40):29426-30. doi: 10.1074/jbc.C600039200. Epub 2006 Aug 25. J Biol Chem. 2006. PMID: 16935858 Free article.

5

A molecular switch that controls cell spreading and retraction.

Flevaris P, Stojanovic A, Gong H, Chishti A, Welch E, Du X. Flevaris P, et al. J Cell Biol. 2007 Nov 5;179(3):553-65. doi: 10.1083/jcb.200703185. Epub 2007 Oct 29. J Cell Biol. 2007. PMID: 17967945 Free PMC article.

6

Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis.

Flevaris P, Khan SS, Eren M, Schuldt AJT, Shah SJ, Lee DC, Gupta S, Shapiro AD, Burridge PW, Ghosh AK, Vaughan DE. Flevaris P, et al. Circulation. 2017 Aug 15;136(7):664-679. doi: 10.1161/CIRCULATIONAHA.117.028145. Epub 2017 Jun 6. Circulation. 2017. PMID: 28588076 Free PMC article.

7

Identification of Cardiac Fibrosis in Young Adults With a Homozygous Frameshift Variant in SERPINE1.

Khan SS, Shah SJ, Strande JL, Baldridge AS, Flevaris P, Puckelwartz MJ, McNally EM, Rasmussen-Torvik LJ, Lee DC, Carr JC, Benefield BC, Afzal MZ, Heiman M, Gupta S, Shapiro AD, Vaughan DE. Khan SS, et al. Among authors: flevaris p. JAMA Cardiol. 2021 Jul 1;6(7):841-846. doi: 10.1001/jamacardio.2020.6909. JAMA Cardiol. 2021. PMID: 33439236 Free PMC article.

8

Epigenetics in Reactive and Reparative Cardiac Fibrogenesis: The Promise of Epigenetic Therapy.

Ghosh AK, Rai R, Flevaris P, Vaughan DE. Ghosh AK, et al. Among authors: flevaris p. J Cell Physiol. 2017 Aug;232(8):1941-1956. doi: 10.1002/jcp.25699. Epub 2017 Feb 28. J Cell Physiol. 2017. PMID: 27883184 Review.

9

PAI-1 is a critical regulator of FGF23 homeostasis.

Eren M, Place AT, Thomas PM, Flevaris P, Miyata T, Vaughan DE. Eren M, et al. Among authors: flevaris p. Sci Adv. 2017 Sep 13;3(9):e1603259. doi: 10.1126/sciadv.1603259. eCollection 2017 Sep. Sci Adv. 2017. PMID: 28924605 Free PMC article.

10

The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis.

Flevaris P, Vaughan D. Flevaris P, et al. Semin Thromb Hemost. 2017 Mar;43(2):169-177. doi: 10.1055/s-0036-1586228. Epub 2016 Aug 24. Semin Thromb Hemost. 2017. PMID: 27556351 Review.

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