Hara K - Search Results

1

Influence of ALDH2 genetic polymorphisms on aciclovir pharmacokinetics following oral administration of valaciclovir in Japanese end-stage renal disease patients.

Hara K, Suyama K, Itoh H, Nagashima S. Hara K, et al. Drug Metab Pharmacokinet. 2008;23(5):306-12. doi: 10.2133/dmpk.23.306. Drug Metab Pharmacokinet. 2008. PMID: 18974607 Free article.

2

Pharmacokinetics, pharmacodynamics and safety of single, oral doses of GSK1278863, a novel HIF-prolyl hydroxylase inhibitor, in healthy Japanese and Caucasian subjects.

Hara K, Takahashi N, Wakamatsu A, Caltabiano S. Hara K, et al. Drug Metab Pharmacokinet. 2015 Dec;30(6):410-8. doi: 10.1016/j.dmpk.2015.08.004. Epub 2015 Aug 28. Drug Metab Pharmacokinet. 2015. PMID: 26643993 Clinical Trial.

3

Comparison of levocetirizine pharmacokinetics after single doses of levocetirizine oral solution and cetirizine dry syrup in healthy Japanese male subjects.

Ino H, Hara K, Honma G, Doi Y, Fukase H. Ino H, et al. Among authors: hara k. J Drug Assess. 2014 Jun 3;3(1):38-42. doi: 10.3109/21556660.2014.928302. eCollection 2014. J Drug Assess. 2014. PMID: 27536452 Free PMC article.

4

Efficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia: A Randomized, Double-Blind, Phase 3 Trial.

Akizawa T, Nangaku M, Yonekawa T, Okuda N, Kawamatsu S, Onoue T, Endo Y, Hara K, Cobitz AR. Akizawa T, et al. Among authors: hara k. Clin J Am Soc Nephrol. 2020 Aug 7;15(8):1155-1165. doi: 10.2215/CJN.16011219. Epub 2020 Jul 28. Clin J Am Soc Nephrol. 2020. PMID: 32723804 Free PMC article. Clinical Trial.

5

Safety and pharmacokinetic evaluation of intravenous colistin methanesulfonate sodium in Japanese healthy male subjects.

Mizuyachi K, Hara K, Wakamatsu A, Nohda S, Hirama T. Mizuyachi K, et al. Among authors: hara k. Curr Med Res Opin. 2011 Dec;27(12):2261-70. doi: 10.1185/03007995.2011.626557. Epub 2011 Oct 14. Curr Med Res Opin. 2011. PMID: 21995648 Clinical Trial.

6

The pharmacokinetic and safety profiles of zanamivir after single and repeat intravenous administration in healthy Japanese males.

Shida Y, Hara K, Nohda S, Soutome T, Hirama T. Shida Y, et al. Among authors: hara k. J Clin Pharm Ther. 2013 Jun;38(3):236-40. doi: 10.1111/jcpt.12056. Epub 2013 Mar 14. J Clin Pharm Ther. 2013. PMID: 23489210 Clinical Trial.

7

Pharmacokinetic and pharmacodynamic analysis of a novel leukotriene biosynthesis inhibitor, MK-0591, in healthy volunteers.

Uematsu T, Kanamaru M, Kosuge K, Hara K, Uchiyama N, Takenaga N, Tanaka W, Friedman BS, Nakashima M. Uematsu T, et al. Among authors: hara k. Br J Clin Pharmacol. 1995 Jul;40(1):59-66. doi: 10.1111/j.1365-2125.1995.tb04535.x. Br J Clin Pharmacol. 1995. PMID: 8527269 Free PMC article. Clinical Trial.

8

Effect of cimetidine on the pharmacokinetics and pharmacodynamics of enalapril in normal volunteers.

Ishizaki T, Baba T, Murabayashi S, Kubota K, Hara K, Kurimoto F. Ishizaki T, et al. Among authors: hara k. J Cardiovasc Pharmacol. 1988;12(5):512-9. doi: 10.1097/00005344-198811000-00003. J Cardiovasc Pharmacol. 1988. PMID: 2468049 Clinical Trial.

9

Time-dependent nephrotoxicity associated with daily administration of cisplatin in mice.

To H, Kikuchi A, Tsuruoka S, Sugimoto K, Fujimura A, Higuchi S, Kayama F, Hara K, Matsuno K, Kobayashi E. To H, et al. Among authors: hara k. J Pharm Pharmacol. 2000 Dec;52(12):1499-504. doi: 10.1211/0022357001777711. J Pharm Pharmacol. 2000. PMID: 11197078

10

Surveys/Research Exploring Japanese Phase I Studies in Global Drug Development: Are They Necessary Prior to Joining Global Clinical Trials?

Hirano M, Yamada M, Tanaka T, Koue T, Saito T, Higashimori M, Ochiai H, Yamamoto J, Yaguchi S, Mita S, Hara K; EFPIA Japan Technical Committee PK/PD Task Force. Hirano M, et al. Among authors: hara k. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1410-1418. doi: 10.1002/cpdd.1044. Epub 2021 Nov 26. Clin Pharmacol Drug Dev. 2021. PMID: 34837487 Free PMC article. No abstract available.

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