Gottesfeld JM - Search Results

1

Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate.

Chou CJ, O'Hare T, Lefebvre S, Alvarez D, Tyner JW, Eide CA, Druker BJ, Gottesfeld JM. Chou CJ, et al. Among authors: gottesfeld jm. PLoS One. 2008;3(10):e3593. doi: 10.1371/journal.pone.0003593. Epub 2008 Oct 31. PLoS One. 2008. PMID: 18974832 Free PMC article.

2

A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.

Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. Alvarez D, et al. Among authors: gottesfeld jm. Cell Cycle. 2006 Jul;5(14):1537-48. doi: 10.4161/cc.5.14.2913. Epub 2006 Jul 17. Cell Cycle. 2006. PMID: 16861886

3

Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.

Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Chou CJ, et al. Among authors: gottesfeld jm. Mol Cancer Ther. 2008 Apr;7(4):769-78. doi: 10.1158/1535-7163.MCT-08-0130. Mol Cancer Ther. 2008. PMID: 18413791 Free PMC article.

4

Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.

Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Tsai SM, et al. Among authors: gottesfeld jm. Nucleic Acids Res. 2007;35(1):307-16. doi: 10.1093/nar/gkl1025. Epub 2006 Dec 14. Nucleic Acids Res. 2007. PMID: 17170006 Free PMC article.

5

Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases.

Chou CJ, Herman D, Gottesfeld JM. Chou CJ, et al. Among authors: gottesfeld jm. J Biol Chem. 2008 Dec 19;283(51):35402-9. doi: 10.1074/jbc.M807045200. Epub 2008 Oct 24. J Biol Chem. 2008. PMID: 18953021 Free PMC article.

6

Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors.

Hu F, Chou CJ, Gottesfeld JM. Hu F, et al. Among authors: gottesfeld jm. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3928-31. doi: 10.1016/j.bmcl.2009.03.085. Epub 2009 Mar 25. Bioorg Med Chem Lett. 2009. PMID: 19362838 Free PMC article.

7

Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.

Soragni E, Chou CJ, Rusche JR, Gottesfeld JM. Soragni E, et al. Among authors: gottesfeld jm. Front Neurol. 2015 Mar 5;6:44. doi: 10.3389/fneur.2015.00044. eCollection 2015. Front Neurol. 2015. PMID: 25798128 Free PMC article.

8

Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing.

Xu C, Soragni E, Chou CJ, Herman D, Plasterer HL, Rusche JR, Gottesfeld JM. Xu C, et al. Among authors: gottesfeld jm. Chem Biol. 2009 Sep 25;16(9):980-9. doi: 10.1016/j.chembiol.2009.07.010. Chem Biol. 2009. PMID: 19778726 Free PMC article.

9

Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes.

Minoshima M, Chou JC, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H. Minoshima M, et al. Among authors: gottesfeld jm. Bioorg Med Chem. 2010 Jan 1;18(1):168-74. doi: 10.1016/j.bmc.2009.11.005. Epub 2009 Nov 11. Bioorg Med Chem. 2010. PMID: 19962902

10

Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells.

Jespersen C, Soragni E, James Chou C, Arora PS, Dervan PB, Gottesfeld JM. Jespersen C, et al. Among authors: gottesfeld jm. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4068-71. doi: 10.1016/j.bmcl.2012.04.090. Epub 2012 Apr 25. Bioorg Med Chem Lett. 2012. PMID: 22607671 Free PMC article.

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