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A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system.
Gulyás B, Makkai B, Kása P, Gulya K, Bakota L, Várszegi S, Beliczai Z, Andersson J, Csiba L, Thiele A, Dyrks T, Suhara T, Suzuki K, Higuchi M, Halldin C. Gulyás B, et al. Among authors: dyrks t. Neurochem Int. 2009 Jan;54(1):28-36. doi: 10.1016/j.neuint.2008.10.001. Epub 2008 Oct 15. Neurochem Int. 2009. PMID: 18984021
The norepinephrine transporter (NET) radioligand (S,S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: a post-mortem autoradiographic study.
Gulyás B, Brockschnieder D, Nag S, Pavlova E, Kása P, Beliczai Z, Légrádi A, Gulya K, Thiele A, Dyrks T, Halldin C. Gulyás B, et al. Among authors: dyrks t. Neurochem Int. 2010 May-Jun;56(6-7):789-98. doi: 10.1016/j.neuint.2010.03.001. Epub 2010 Mar 6. Neurochem Int. 2010. PMID: 20211213 Free article.
Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects.
Varrone A, Oikonen V, Forsberg A, Joutsa J, Takano A, Solin O, Haaparanta-Solin M, Nag S, Nakao R, Al-Tawil N, Wells LA, Rabiner EA, Valencia R, Schultze-Mosgau M, Thiele A, Vollmer S, Dyrks T, Lehmann L, Heinrich T, Hoffmann A, Nordberg A, Halldin C, Rinne JO. Varrone A, et al. Among authors: dyrks t. Eur J Nucl Med Mol Imaging. 2015 Mar;42(3):438-46. doi: 10.1007/s00259-014-2955-8. Epub 2014 Nov 21. Eur J Nucl Med Mol Imaging. 2015. PMID: 25412766 Clinical Trial.
Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β.
Brockschnieder D, Schmitt-Willich H, Heinrich T, Varrone A, Gulyás B, Toth M, Andersson J, Boemer U, Krause S, Friebe M, Dinkelborg L, Halldin C, Dyrks T. Brockschnieder D, et al. Among authors: dyrks t. J Nucl Med. 2012 Nov;53(11):1794-801. doi: 10.2967/jnumed.112.104810. Epub 2012 Sep 24. J Nucl Med. 2012. PMID: 23008501 Free article.
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.
Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki HW, Maler M, Dyrks T, Bienert M, Beyermann M, Rüther E, Kornhuber J. Wiltfang J, et al. Among authors: dyrks t. J Neurochem. 2002 May;81(3):481-96. doi: 10.1046/j.1471-4159.2002.00818.x. J Neurochem. 2002. PMID: 12065657 Free article.
In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer.
Fodero-Tavoletti MT, Brockschnieder D, Villemagne VL, Martin L, Connor AR, Thiele A, Berndt M, McLean CA, Krause S, Rowe CC, Masters CL, Dinkelborg L, Dyrks T, Cappai R. Fodero-Tavoletti MT, et al. Among authors: dyrks t. Nucl Med Biol. 2012 Oct;39(7):1042-8. doi: 10.1016/j.nucmedbio.2012.03.001. Epub 2012 Apr 11. Nucl Med Biol. 2012. PMID: 22503458
30 results