Conley JM - Search Results

1

A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.

Willard FS, Zheng Z, Guo J, Digby GJ, Kimple AJ, Conley JM, Johnston CA, Bosch D, Willard MD, Watts VJ, Lambert NA, Ikeda SR, Du Q, Siderovski DP. Willard FS, et al. Among authors: conley jm. J Biol Chem. 2008 Dec 26;283(52):36698-710. doi: 10.1074/jbc.M804936200. Epub 2008 Nov 4. J Biol Chem. 2008. PMID: 18984596 Free PMC article.

2

Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D₃ receptor-selective full agonist ligand.

Clark AH, McCorvy JD, Conley JM, Williams WK, Bekkam M, Watts VJ, Nichols DE. Clark AH, et al. Among authors: conley jm. Bioorg Med Chem. 2012 Nov 1;20(21):6366-74. doi: 10.1016/j.bmc.2012.08.058. Epub 2012 Sep 8. Bioorg Med Chem. 2012. PMID: 23018094 Free PMC article.

3

Bimolecular fluorescence complementation analysis of G protein-coupled receptor dimerization in living cells.

Ejendal KF, Conley JM, Hu CD, Watts VJ. Ejendal KF, et al. Among authors: conley jm. Methods Enzymol. 2013;521:259-79. doi: 10.1016/B978-0-12-391862-8.00014-4. Methods Enzymol. 2013. PMID: 23351744

4

Differential effects of AGS3 expression on D(2L) dopamine receptor-mediated adenylyl cyclase signaling.

Conley JM, Watts VJ. Conley JM, et al. Cell Mol Neurobiol. 2013 May;33(4):551-8. doi: 10.1007/s10571-013-9925-8. Epub 2013 Mar 17. Cell Mol Neurobiol. 2013. PMID: 23504261 Free PMC article.

5

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor.

Conley JM, Brand CS, Bogard AS, Pratt EP, Xu R, Hockerman GH, Ostrom RS, Dessauer CW, Watts VJ. Conley JM, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):276-87. doi: 10.1124/jpet.113.207449. Epub 2013 Sep 5. J Pharmacol Exp Ther. 2013. PMID: 24008337 Free PMC article.

6

Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications.

Conley JM, Brust TF, Xu R, Burris KD, Watts VJ. Conley JM, et al. J Vis Exp. 2014 Jan 27;(83):e51218. doi: 10.3791/51218. J Vis Exp. 2014. PMID: 24514897 Free PMC article.

7

Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.

Conley JM, Meyer JM, Nuss AB, Doyle TB, Savinov SN, Hill CA, Watts VJ. Conley JM, et al. J Pharmacol Exp Ther. 2015 Jan;352(1):53-60. doi: 10.1124/jpet.114.219717. Epub 2014 Oct 20. J Pharmacol Exp Ther. 2015. PMID: 25332454 Free PMC article.

8

Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later.

Brust TF, Conley JM, Watts VJ. Brust TF, et al. Among authors: conley jm. Eur J Pharmacol. 2015 Sep 15;763(Pt B):223-32. doi: 10.1016/j.ejphar.2015.05.014. Epub 2015 May 14. Eur J Pharmacol. 2015. PMID: 25981304 Free PMC article. Review.

9

Molecular Modeling Evaluation of the Enantiomers of a Novel Adenylyl Cyclase 2 Inhibitor.

Rana N, Conley JM, Soto-Velasquez M, León F, Cutler SJ, Watts VJ, Lill MA. Rana N, et al. Among authors: conley jm. J Chem Inf Model. 2017 Feb 27;57(2):322-334. doi: 10.1021/acs.jcim.6b00454. Epub 2017 Jan 26. J Chem Inf Model. 2017. PMID: 28068084

10

G protein-coupled receptor 17 inhibits glucagon-like peptide-1 secretion via a Gi/o-dependent mechanism in enteroendocrine cells.

Conley JM, Jochim A, Evans-Molina C, Watts VJ, Ren H. Conley JM, et al. bioRxiv [Preprint]. 2024 Nov 13:2024.11.13.623413. doi: 10.1101/2024.11.13.623413. bioRxiv. 2024. PMID: 39605686 Free PMC article. Preprint.

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