de Jong SD - Search Results

1

The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine.

Wilson KD, de Jong SD, Kazem M, Lall R, Hope MJ, Cullis PR, Tam YK. Wilson KD, et al. Among authors: de jong sd. J Gene Med. 2009 Jan;11(1):14-25. doi: 10.1002/jgm.1267. J Gene Med. 2009. PMID: 19003796

2

Effects of intravenous and subcutaneous administration on the pharmacokinetics, biodistribution, cellular uptake and immunostimulatory activity of CpG ODN encapsulated in liposomal nanoparticles.

Wilson KD, Raney SG, Sekirov L, Chikh G, deJong SD, Cullis PR, Tam YK. Wilson KD, et al. Int Immunopharmacol. 2007 Aug;7(8):1064-75. doi: 10.1016/j.intimp.2007.04.002. Epub 2007 May 2. Int Immunopharmacol. 2007. PMID: 17570323

3

The effect of circulation lifetime and drug-to-lipid ratio of intravenously administered lipid nanoparticles on the biodistribution and immunostimulatory activity of encapsulated CpG-ODN.

Raney SG, Wilson KD, Sekirov L, Chikh G, de Jong SD, Cullis PR, Tam YK. Raney SG, et al. Among authors: de jong sd. J Drug Target. 2008 Aug;16(7):564-77. doi: 10.1080/10611860802228756. J Drug Target. 2008. PMID: 18686126

4

Lipid-based delivery of CpG oligonucleotides enhances immunotherapeutic efficacy.

Wilson KD, de Jong SD, Tam YK. Wilson KD, et al. Among authors: de jong sd. Adv Drug Deliv Rev. 2009 Mar 28;61(3):233-42. doi: 10.1016/j.addr.2008.12.014. Epub 2009 Feb 13. Adv Drug Deliv Rev. 2009. PMID: 19232375 Review.

5

Synthetic methylated CpG ODNs are potent in vivo adjuvants when delivered in liposomal nanoparticles.

Chikh G, de Jong SD, Sekirov L, Raney SG, Kazem M, Wilson KD, Cullis PR, Dutz JP, Tam YK. Chikh G, et al. Among authors: de jong sd. Int Immunol. 2009 Jul;21(7):757-67. doi: 10.1093/intimm/dxp044. Epub 2009 Jun 5. Int Immunol. 2009. PMID: 19502586

6

The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes.

de Jong SD, Basha G, Wilson KD, Kazem M, Cullis P, Jefferies W, Tam Y. de Jong SD, et al. J Immunol. 2010 Jun 1;184(11):6092-102. doi: 10.4049/jimmunol.0802442. Epub 2010 Apr 28. J Immunol. 2010. PMID: 20427776

7

Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN.

de Jong S, Chikh G, Sekirov L, Raney S, Semple S, Klimuk S, Yuan N, Hope M, Cullis P, Tam Y. de Jong S, et al. Cancer Immunol Immunother. 2007 Aug;56(8):1251-64. doi: 10.1007/s00262-006-0276-x. Epub 2007 Jan 23. Cancer Immunol Immunother. 2007. PMID: 17242927 Free PMC article.

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