FitzGerald DJ - Search Results

1

Barnase toxin: a new chimeric toxin composed of pseudomonas exotoxin A and barnase.

Prior TI, FitzGerald DJ, Pastan I. Prior TI, et al. Among authors: fitzgerald dj. Cell. 1991 Mar 8;64(5):1017-23. doi: 10.1016/0092-8674(91)90325-s. Cell. 1991. PMID: 1900455

2

Biological activity of a transforming growth factor-alpha--Pseudomonas exotoxin fusion protein in vitro and in vivo.

Heimbrook DC, Stirdivant SM, Ahern JD, Balishin NL, Patrick DR, Edwards GM, Defeo-Jones D, FitzGerald DJ, Pastan I, Oliff A. Heimbrook DC, et al. Among authors: fitzgerald dj. J Ind Microbiol. 1991 Apr;7(3):203-7. doi: 10.1007/BF01575884. J Ind Microbiol. 1991. PMID: 1367127

3

Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor.

Kreitman RJ, Schneider WP, Queen C, Tsudo M, Fitzgerald DJ, Waldmann TA, Pastan I. Kreitman RJ, et al. Among authors: fitzgerald dj. J Immunol. 1992 Oct 15;149(8):2810-5. J Immunol. 1992. PMID: 1401913

4

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.

Kreitman RJ, Chaudhary VK, Kozak RW, FitzGerald DJ, Waldman TA, Pastan I. Kreitman RJ, et al. Among authors: fitzgerald dj. Blood. 1992 Nov 1;80(9):2344-52. Blood. 1992. PMID: 1421405 Free article.

5

Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.

Ogata M, Fryling CM, Pastan I, FitzGerald DJ. Ogata M, et al. Among authors: fitzgerald dj. J Biol Chem. 1992 Dec 15;267(35):25396-401. J Biol Chem. 1992. PMID: 1460035 Free article.

6

Pseudomonas exotoxin: recombinant conjugates as therapeutic agents.

FitzGerald DJ, Pastan I. FitzGerald DJ, et al. Biochem Soc Trans. 1992 Nov;20(4):731-4. doi: 10.1042/bst0200731. Biochem Soc Trans. 1992. PMID: 1487051 Review. No abstract available.

7

Recombinant toxins as novel therapeutic agents.

Pastan I, Chaudhary V, FitzGerald DJ. Pastan I, et al. Among authors: fitzgerald dj. Annu Rev Biochem. 1992;61:331-54. doi: 10.1146/annurev.bi.61.070192.001555. Annu Rev Biochem. 1992. PMID: 1497314 Review. No abstract available.

8

Alteration of a protease-sensitive region of Pseudomonas exotoxin prolongs its survival in the circulation of mice.

Brinkmann U, Pai LH, FitzGerald DJ, Pastan I. Brinkmann U, et al. Among authors: fitzgerald dj. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3065-9. doi: 10.1073/pnas.89.7.3065. Proc Natl Acad Sci U S A. 1992. PMID: 1557414 Free PMC article.

9

Interleukin-6 fused to a mutant form of Pseudomonas exotoxin kills malignant cells from patients with multiple myeloma.

Kreitman RJ, Siegall CB, FitzGerald DJ, Epstein J, Barlogie B, Pastan I. Kreitman RJ, et al. Among authors: fitzgerald dj. Blood. 1992 Apr 1;79(7):1775-80. Blood. 1992. PMID: 1558971 Free article.

10

Translocation mediated by domain II of Pseudomonas exotoxin A: transport of barnase into the cytosol.

Prior TI, FitzGerald DJ, Pastan I. Prior TI, et al. Among authors: fitzgerald dj. Biochemistry. 1992 Apr 14;31(14):3555-9. doi: 10.1021/bi00129a001. Biochemistry. 1992. PMID: 1567815

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