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Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH.
Kimura Y, Hyogo H, Yamagishi S, Takeuchi M, Ishitobi T, Nabeshima Y, Arihiro K, Chayama K. Kimura Y, et al. Among authors: ishitobi t. J Gastroenterol. 2010 Jul;45(7):750-7. doi: 10.1007/s00535-010-0203-y. Epub 2010 Jan 30. J Gastroenterol. 2010. PMID: 20112031 Clinical Trial.
A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion.
Nishioka T, Hyogo H, Numata Y, Yamaguchi A, Kobuke T, Komichi D, Nonaka M, Inoue M, Nabeshima Y, Ogi M, Iwamoto K, Ishitobi T, Ajima T, Chayama K, Tazuma S. Nishioka T, et al. Among authors: ishitobi t. J Atheroscler Thromb. 2005;12(4):211-7. doi: 10.5551/jat.12.211. J Atheroscler Thromb. 2005. PMID: 16141625 Free article.
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