Nakabeppu Y - Search Results

1

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

De Luca G, Russo MT, Degan P, Tiveron C, Zijno A, Meccia E, Ventura I, Mattei E, Nakabeppu Y, Crescenzi M, Pepponi R, Pèzzola A, Popoli P, Bignami M. De Luca G, et al. Among authors: nakabeppu y. PLoS Genet. 2008 Nov;4(11):e1000266. doi: 10.1371/journal.pgen.1000266. Epub 2008 Nov 21. PLoS Genet. 2008. PMID: 19023407 Free PMC article.

2

The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells.

Russo MT, Blasi MF, Chiera F, Fortini P, Degan P, Macpherson P, Furuichi M, Nakabeppu Y, Karran P, Aquilina G, Bignami M. Russo MT, et al. Among authors: nakabeppu y. Mol Cell Biol. 2004 Jan;24(1):465-74. doi: 10.1128/MCB.24.1.465-474.2004. Mol Cell Biol. 2004. PMID: 14673178 Free PMC article.

3

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes.

Haruyama N, Sakumi K, Katogi A, Tsuchimoto D, De Luca G, Bignami M, Nakabeppu Y. Haruyama N, et al. Among authors: nakabeppu y. Prog Neurobiol. 2019 Sep;180:101613. doi: 10.1016/j.pneurobio.2019.04.002. Epub 2019 Apr 23. Prog Neurobiol. 2019. PMID: 31026482 Free article.

4

Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.

Evans MD, Mistry V, Singh R, Gackowski D, Różalski R, Siomek-Gorecka A, Phillips DH, Zuo J, Mullenders L, Pines A, Nakabeppu Y, Sakumi K, Sekiguchi M, Tsuzuki T, Bignami M, Oliński R, Cooke MS. Evans MD, et al. Among authors: nakabeppu y. Free Radic Biol Med. 2016 Oct;99:385-391. doi: 10.1016/j.freeradbiomed.2016.08.018. Epub 2016 Aug 30. Free Radic Biol Med. 2016. PMID: 27585947

5

MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration.

Murakami Y, Ikeda Y, Yoshida N, Notomi S, Hisatomi T, Oka S, De Luca G, Yonemitsu Y, Bignami M, Nakabeppu Y, Ishibashi T. Murakami Y, et al. Among authors: nakabeppu y. Am J Pathol. 2012 Oct;181(4):1378-86. doi: 10.1016/j.ajpath.2012.06.026. Epub 2012 Jul 27. Am J Pathol. 2012. PMID: 22841817 Free article.

6

8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.

Sheng Z, Oka S, Tsuchimoto D, Abolhassani N, Nomaru H, Sakumi K, Yamada H, Nakabeppu Y. Sheng Z, et al. Among authors: nakabeppu y. J Clin Invest. 2012 Dec;122(12):4344-61. doi: 10.1172/JCI65053. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143307 Free PMC article.

7

Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.

Nakabeppu Y, Oka S, Sheng Z, Tsuchimoto D, Sakumi K. Nakabeppu Y, et al. Mutat Res. 2010 Nov 28;703(1):51-8. doi: 10.1016/j.mrgentox.2010.06.006. Epub 2010 Jun 11. Mutat Res. 2010. PMID: 20542142 Free article. Review.

8

MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.

Nakabeppu Y, Kajitani K, Sakamoto K, Yamaguchi H, Tsuchimoto D. Nakabeppu Y, et al. DNA Repair (Amst). 2006 Jul 13;5(7):761-72. doi: 10.1016/j.dnarep.2006.03.003. Epub 2006 Apr 18. DNA Repair (Amst). 2006. PMID: 16621731 Review.

9

Oxidative damage in nucleic acids and Parkinson's disease.

Nakabeppu Y, Tsuchimoto D, Yamaguchi H, Sakumi K. Nakabeppu Y, et al. J Neurosci Res. 2007 Apr;85(5):919-34. doi: 10.1002/jnr.21191. J Neurosci Res. 2007. PMID: 17279544 Free article. Review.

10

MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Yamaguchi H, Kajitani K, Dan Y, Furuichi M, Ohno M, Sakumi K, Kang D, Nakabeppu Y. Yamaguchi H, et al. Among authors: nakabeppu y. Cell Death Differ. 2006 Apr;13(4):551-63. doi: 10.1038/sj.cdd.4401788. Cell Death Differ. 2006. PMID: 16273081

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