Axelson M - Search Results

1

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.

Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A. Economou MA, et al. Among authors: axelson m. Acta Ophthalmol. 2008 Nov;86 Thesis 4:42-9. doi: 10.1111/j.1755-3768.2008.01185.x. Acta Ophthalmol. 2008. PMID: 19032681 Free article.

2

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.

Vasilcanu D, Girnita A, Girnita L, Vasilcanu R, Axelson M, Larsson O. Vasilcanu D, et al. Among authors: axelson m. Oncogene. 2004 Oct 14;23(47):7854-62. doi: 10.1038/sj.onc.1208065. Oncogene. 2004. PMID: 15334055

3

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.

Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L. Girnita A, et al. Among authors: axelson m. Clin Cancer Res. 2006 Feb 15;12(4):1383-91. doi: 10.1158/1078-0432.CCR-05-1106. Clin Cancer Res. 2006. PMID: 16489097

4

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.

Razuvaev A, Henderson B, Girnita L, Larsson O, Axelson M, Hedin U, Roy J. Razuvaev A, et al. Among authors: axelson m. J Vasc Surg. 2007 Jul;46(1):108-15. doi: 10.1016/j.jvs.2007.02.066. J Vasc Surg. 2007. PMID: 17606126 Free article.

5

Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.

Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L. Vasilcanu R, et al. Among authors: axelson m. Mol Pharmacol. 2008 Mar;73(3):930-9. doi: 10.1124/mol.107.040014. Epub 2007 Dec 10. Mol Pharmacol. 2008. PMID: 18070930

6

Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.

Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O. Economou MA, et al. Among authors: axelson m. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2337-42. doi: 10.1167/iovs.07-0819. Invest Ophthalmol Vis Sci. 2008. PMID: 18515579

7

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.

Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A. Economou MA, et al. Among authors: axelson m. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2620-6. doi: 10.1167/iovs.07-0742. Invest Ophthalmol Vis Sci. 2008. PMID: 18515591

8

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.

Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L. Girnita A, et al. Among authors: axelson m. Acta Ophthalmol. 2008 Nov;86 Thesis 4:26-34. doi: 10.1111/j.1755-3768.2008.01183.x. Acta Ophthalmol. 2008. PMID: 19032679 Free article.

9

Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.

Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O. Economou MA, et al. Among authors: axelson m. Acta Ophthalmol. 2008 Nov;86 Thesis 4:35-41. doi: 10.1111/j.1755-3768.2008.01184.x. Acta Ophthalmol. 2008. PMID: 19032680 Free article.

10

Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma.

Yin S, Girnita A, Strömberg T, Khan Z, Andersson S, Zheng H, Ericsson C, Axelson M, Nistér M, Larsson O, Ekström TJ, Girnita L. Yin S, et al. Among authors: axelson m. Neuro Oncol. 2010 Jan;12(1):19-27. doi: 10.1093/neuonc/nop008. Epub 2009 Oct 20. Neuro Oncol. 2010. PMID: 20150364 Free PMC article.

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