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The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells.
Roelofs MF, Joosten LA, Abdollahi-Roodsaz S, van Lieshout AW, Sprong T, van den Hoogen FH, van den Berg WB, Radstake TR. Roelofs MF, et al. Among authors: radstake tr. Arthritis Rheum. 2005 Aug;52(8):2313-22. doi: 10.1002/art.21278. Arthritis Rheum. 2005. PMID: 16052591 Free article.
Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis.
Popa C, van den Hoogen FH, Radstake TR, Netea MG, Eijsbouts AE, den Heijer M, van der Meer JW, van Riel PL, Stalenhoef AF, Barrera P. Popa C, et al. Among authors: radstake tr. Ann Rheum Dis. 2007 Nov;66(11):1503-7. doi: 10.1136/ard.2006.066191. Epub 2007 May 1. Ann Rheum Dis. 2007. PMID: 17472994 Free PMC article. Clinical Trial.
Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.
Zhernakova A, Alizadeh BZ, Bevova M, van Leeuwen MA, Coenen MJ, Franke B, Franke L, Posthumus MD, van Heel DA, van der Steege G, Radstake TR, Barrera P, Roep BO, Koeleman BP, Wijmenga C. Zhernakova A, et al. Among authors: radstake tr. Am J Hum Genet. 2007 Dec;81(6):1284-8. doi: 10.1086/522037. Epub 2007 Oct 24. Am J Hum Genet. 2007. PMID: 17999365 Free PMC article.
355 results