Altmann KH - Search Results

1

Total synthesis of the marine diterpenoid blumiolide C.

Hamel C, Prusov EV, Gertsch J, Schweizer WB, Altmann KH. Hamel C, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2008;47(52):10081-5. doi: 10.1002/anie.200804004. Angew Chem Int Ed Engl. 2008. PMID: 19039812 No abstract available.

2

Scaffolds for microtubule inhibition through extensive modification of the epothilone template.

Cachoux F, Isarno T, Wartmann M, Altmann KH. Cachoux F, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2005 Dec 1;44(45):7469-73. doi: 10.1002/anie.200501760. Angew Chem Int Ed Engl. 2005. PMID: 16240301 No abstract available.

3

Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.

Raduner S, Majewska A, Chen JZ, Xie XQ, Hamon J, Faller B, Altmann KH, Gertsch J. Raduner S, et al. Among authors: altmann kh. J Biol Chem. 2006 May 19;281(20):14192-206. doi: 10.1074/jbc.M601074200. Epub 2006 Mar 17. J Biol Chem. 2006. PMID: 16547349 Free article.

4

Design and synthesis of 12-aza-epothilones (azathilones)--"non-natural" natural products with potent anticancer activity.

Feyen F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5880-5. doi: 10.1002/anie.200601359. Angew Chem Int Ed Engl. 2006. PMID: 16871640 No abstract available.

5

Structure-activity relationships in side-chain-modified epothilone analogues--how important is the position of the nitrogen atom?

Bold G, Wojeik S, Caravatti G, Lindauer R, Stierlin C, Gertsch J, Wartmann M, Altmann KH. Bold G, et al. Among authors: altmann kh. ChemMedChem. 2006 Jan;1(1):37-40. doi: 10.1002/cmdc.200500051. ChemMedChem. 2006. PMID: 16892331 No abstract available.

6

New natural noncannabinoid ligands for cannabinoid type-2 (CB2) receptors.

Gertsch J, Raduner S, Altmann KH. Gertsch J, et al. Among authors: altmann kh. J Recept Signal Transduct Res. 2006;26(5-6):709-30. doi: 10.1080/10799890600942674. J Recept Signal Transduct Res. 2006. PMID: 17118807 Review.

7

Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.

Altmann KH, Gertsch J. Altmann KH, et al. Nat Prod Rep. 2007 Apr;24(2):327-57. doi: 10.1039/b515619j. Epub 2007 Mar 8. Nat Prod Rep. 2007. PMID: 17390000 Review.

8

Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides.

Raduner S, Bisson W, Abagyan R, Altmann KH, Gertsch J. Raduner S, et al. Among authors: altmann kh. J Nat Prod. 2007 Jun;70(6):1010-5. doi: 10.1021/np060598+. Epub 2007 May 11. J Nat Prod. 2007. PMID: 17497806

9

Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.

Feyen F, Cachoux F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: altmann kh. Acc Chem Res. 2008 Jan;41(1):21-31. doi: 10.1021/ar700157x. Epub 2007 Dec 27. Acc Chem Res. 2008. PMID: 18159935 Review.

10

Conformational preferences of natural and C3-modified epothilones in aqueous solution.

Erdélyi M, Pfeiffer B, Hauenstein K, Fohrer J, Gertsch J, Altmann KH, Carlomagno T. Erdélyi M, et al. Among authors: altmann kh. J Med Chem. 2008 Mar 13;51(5):1469-73. doi: 10.1021/jm7013452. Epub 2008 Feb 14. J Med Chem. 2008. PMID: 18271516

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