Wang S - Search Results

1

Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases.

Peng Y, Sun H, Nikolovska-Coleska Z, Qiu S, Yang CY, Lu J, Cai Q, Yi H, Kang S, Yang D, Wang S. Peng Y, et al. Among authors: wang s. J Med Chem. 2008 Dec 25;51(24):8158-62. doi: 10.1021/jm801254r. J Med Chem. 2008. PMID: 19049347 Free PMC article.

2

Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.

Enyedy IJ, Wang J, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang j, wang s. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1775-8. doi: 10.1016/s0960-894x(02)00243-3. Bioorg Med Chem Lett. 2002. PMID: 12067559

3

Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors.

Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang s. Bioorg Med Chem Lett. 2003 Feb 10;13(3):513-7. doi: 10.1016/s0960-894x(02)00943-5. Bioorg Med Chem Lett. 2003. PMID: 12565962

4

Comparative evaluation of 11 scoring functions for molecular docking.

Wang R, Lu Y, Wang S. Wang R, et al. Among authors: wang s. J Med Chem. 2003 Jun 5;46(12):2287-303. doi: 10.1021/jm0203783. J Med Chem. 2003. PMID: 12773034

5

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.

Zhang M, Liu H, Guo R, Ling Y, Wu X, Li B, Roller PP, Wang S, Yang D. Zhang M, et al. Among authors: wang s. Biochem Pharmacol. 2003 Jul 1;66(1):93-103. doi: 10.1016/s0006-2952(03)00248-x. Biochem Pharmacol. 2003. PMID: 12818369

6

Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

Varady J, Wu X, Fang X, Min J, Hu Z, Levant B, Wang S. Varady J, et al. Among authors: wang s. J Med Chem. 2003 Oct 9;46(21):4377-92. doi: 10.1021/jm030085p. J Med Chem. 2003. PMID: 14521403

7

Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists.

Wang S, Yang D, Lippman ME. Wang S, et al. Semin Oncol. 2003 Oct;30(5 Suppl 16):133-42. doi: 10.1053/j.seminoncol.2003.08.015. Semin Oncol. 2003. PMID: 14613034 Review.

8

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Nikolovska-Coleska Z, et al. Among authors: wang s, wang r. J Med Chem. 2004 May 6;47(10):2430-40. doi: 10.1021/jm030420+. J Med Chem. 2004. PMID: 15115387

9

The PDBbind database: collection of binding affinities for protein-ligand complexes with known three-dimensional structures.

Wang R, Fang X, Lu Y, Wang S. Wang R, et al. Among authors: wang s. J Med Chem. 2004 Jun 3;47(12):2977-80. doi: 10.1021/jm030580l. J Med Chem. 2004. PMID: 15163179

10

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. J Med Chem. 2004 Aug 12;47(17):4147-50. doi: 10.1021/jm0499108. J Med Chem. 2004. PMID: 15293984

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