Astapova I - Search Results

1

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo.

Astapova I, Lee LJ, Morales C, Tauber S, Bilban M, Hollenberg AN. Astapova I, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19544-9. doi: 10.1073/pnas.0804604105. Epub 2008 Dec 3. Proc Natl Acad Sci U S A. 2008. PMID: 19052228 Free PMC article.

2

The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.

Hodgson MC, Astapova I, Cheng S, Lee LJ, Verhoeven MC, Choi E, Balk SP, Hollenberg AN. Hodgson MC, et al. Among authors: astapova i. J Biol Chem. 2005 Feb 25;280(8):6511-9. doi: 10.1074/jbc.M408972200. Epub 2004 Dec 14. J Biol Chem. 2005. PMID: 15598662 Free article.

3

Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells.

Blumberg JM, Tzameli I, Astapova I, Lam FS, Flier JS, Hollenberg AN. Blumberg JM, et al. Among authors: astapova i. J Biol Chem. 2006 Apr 21;281(16):11205-13. doi: 10.1074/jbc.M510343200. Epub 2006 Feb 8. J Biol Chem. 2006. PMID: 16467308 Free article.

4

Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.

Hodgson MC, Astapova I, Hollenberg AN, Balk SP. Hodgson MC, et al. Among authors: astapova i. Cancer Res. 2007 Sep 1;67(17):8388-95. doi: 10.1158/0008-5472.CAN-07-0617. Cancer Res. 2007. PMID: 17804755

5

The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains.

Astapova I, Dordek MF, Hollenberg AN. Astapova I, et al. Mol Cell Endocrinol. 2009 Aug 13;307(1-2):83-8. doi: 10.1016/j.mce.2009.02.028. Epub 2009 Mar 9. Mol Cell Endocrinol. 2009. PMID: 19524130

6

Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.

Adams AC, Astapova I, Fisher FM, Badman MK, Kurgansky KE, Flier JS, Hollenberg AN, Maratos-Flier E. Adams AC, et al. Among authors: astapova i. J Biol Chem. 2010 May 7;285(19):14078-82. doi: 10.1074/jbc.C110.107375. Epub 2010 Mar 17. J Biol Chem. 2010. PMID: 20236931 Free PMC article.

7

The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis.

Astapova I, Vella KR, Ramadoss P, Holtz KA, Rodwin BA, Liao XH, Weiss RE, Rosenberg MA, Rosenzweig A, Hollenberg AN. Astapova I, et al. Mol Endocrinol. 2011 Feb;25(2):212-24. doi: 10.1210/me.2010-0462. Epub 2011 Jan 14. Mol Endocrinol. 2011. PMID: 21239618 Free PMC article.

8

Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).

Fozzatti L, Lu C, Kim DW, Park JW, Astapova I, Gavrilova O, Willingham MC, Hollenberg AN, Cheng SY. Fozzatti L, et al. Among authors: astapova i. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17462-7. doi: 10.1073/pnas.1107474108. Epub 2011 Oct 10. Proc Natl Acad Sci U S A. 2011. PMID: 21987803 Free PMC article.

9

The in vivo role of nuclear receptor corepressors in thyroid hormone action.

Astapova I, Hollenberg AN. Astapova I, et al. Biochim Biophys Acta. 2013 Jul;1830(7):3876-81. doi: 10.1016/j.bbagen.2012.07.001. Epub 2012 Jul 16. Biochim Biophys Acta. 2013. PMID: 22801336 Free PMC article. Review.

10

The thyroid axis is regulated by NCoR1 via its actions in the pituitary.

Costa-e-Sousa RH, Astapova I, Ye F, Wondisford FE, Hollenberg AN. Costa-e-Sousa RH, et al. Among authors: astapova i. Endocrinology. 2012 Oct;153(10):5049-57. doi: 10.1210/en.2012-1504. Epub 2012 Aug 9. Endocrinology. 2012. PMID: 22878400 Free PMC article.

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