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Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
Timpson NJ, Lindgren CM, Weedon MN, Randall J, Ouwehand WH, Strachan DP, Rayner NW, Walker M, Hitman GA, Doney AS, Palmer CN, Morris AD, Hattersley AT, Zeggini E, Frayling TM, McCarthy MI. Timpson NJ, et al. Among authors: walker m. Diabetes. 2009 Feb;58(2):505-10. doi: 10.2337/db08-0906. Epub 2008 Dec 3. Diabetes. 2009. PMID: 19056611 Free PMC article.
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM. Gloyn AL, et al. Among authors: walker m. Diabetes. 2003 Feb;52(2):568-72. doi: 10.2337/diabetes.52.2.568. Diabetes. 2003. PMID: 12540637
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility.
Weedon MN, Schwarz PE, Horikawa Y, Iwasaki N, Illig T, Holle R, Rathmann W, Selisko T, Schulze J, Owen KR, Evans J, Del Bosque-Plata L, Hitman G, Walker M, Levy JC, Sampson M, Bell GI, McCarthy MI, Hattersley AT, Frayling TM. Weedon MN, et al. Among authors: walker m. Am J Hum Genet. 2003 Nov;73(5):1208-12. doi: 10.1086/379285. Am J Hum Genet. 2003. PMID: 14574648 Free PMC article. No abstract available.
7,099 results