Gems D - Search Results

1

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans.

Doonan R, McElwee JJ, Matthijssens F, Walker GA, Houthoofd K, Back P, Matscheski A, Vanfleteren JR, Gems D. Doonan R, et al. Among authors: gems d. Genes Dev. 2008 Dec 1;22(23):3236-41. doi: 10.1101/gad.504808. Genes Dev. 2008. PMID: 19056880 Free PMC article.

2

An integrated theory of ageing in the nematode Caenorhabditis elegans.

Gems D. Gems D. J Anat. 2000 Nov;197 Pt 4(Pt 4):521-8. doi: 10.1046/j.1469-7580.2000.19740521.x. J Anat. 2000. PMID: 11197524 Free PMC article.

3

No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8.

Keaney M, Gems D. Keaney M, et al. Among authors: gems d. Free Radic Biol Med. 2003 Jan 15;34(2):277-82. doi: 10.1016/s0891-5849(02)01290-x. Free Radic Biol Med. 2003. PMID: 12521609

4

Body size, insulin/IGF signaling and aging in the nematode Caenorhabditis elegans.

McCulloch D, Gems D. McCulloch D, et al. Among authors: gems d. Exp Gerontol. 2003 Jan-Feb;38(1-2):129-36. doi: 10.1016/s0531-5565(02)00147-x. Exp Gerontol. 2003. PMID: 12543270

5

Ageing: Microarraying mortality.

Gems D, McElwee JJ. Gems D, et al. Nature. 2003 Jul 17;424(6946):259-61. doi: 10.1038/424259a. Nature. 2003. PMID: 12867961 No abstract available.

6

Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans.

Keaney M, Matthijssens F, Sharpe M, Vanfleteren J, Gems D. Keaney M, et al. Among authors: gems d. Free Radic Biol Med. 2004 Jul 15;37(2):239-50. doi: 10.1016/j.freeradbiomed.2004.04.005. Free Radic Biol Med. 2004. PMID: 15203195

7

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance.

McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D. McElwee JJ, et al. Among authors: gems d. J Biol Chem. 2004 Oct 22;279(43):44533-43. doi: 10.1074/jbc.M406207200. Epub 2004 Aug 11. J Biol Chem. 2004. PMID: 15308663 Free article.

8

Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?

Gems D, McElwee JJ. Gems D, et al. Mech Ageing Dev. 2005 Mar;126(3):381-7. doi: 10.1016/j.mad.2004.09.001. Mech Ageing Dev. 2005. PMID: 15664624 Review.

9

Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways.

Walker G, Houthoofd K, Vanfleteren JR, Gems D. Walker G, et al. Among authors: gems d. Mech Ageing Dev. 2005 Sep;126(9):929-37. doi: 10.1016/j.mad.2005.03.014. Mech Ageing Dev. 2005. PMID: 15896824 Review.

10

LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans.

Nanji M, Hopper NA, Gems D. Nanji M, et al. Among authors: gems d. Aging Cell. 2005 Oct;4(5):235-45. doi: 10.1111/j.1474-9726.2005.00166.x. Aging Cell. 2005. PMID: 16164423 Free article.

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