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Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study.
Keystone EC, Genovese MC, Klareskog L, Hsia EC, Hall ST, Miranda PC, Pazdur J, Bae SC, Palmer W, Zrubek J, Wiekowski M, Visvanathan S, Wu Z, Rahman MU; GO-FORWARD Study. Keystone EC, et al. Among authors: wiekowski m. Ann Rheum Dis. 2009 Jun;68(6):789-96. doi: 10.1136/ard.2008.099010. Epub 2008 Dec 9. Ann Rheum Dis. 2009. PMID: 19066176 Free PMC article. Clinical Trial.
Immunomodulatory and clinical effects of receptor-interacting protein kinase 1 (RIPK1) inhibitor eclitasertib (SAR443122) in patients with severe COVID-19: a phase 1b, randomized, double-blinded, placebo-controlled study.
Clot PF, Farenc C, Suratt BT, Krahnke T, Tardat A, Florian P, Pomponio R, Patel N, Wiekowski M, Lin Y, Terrier B, Staudinger H. Clot PF, et al. Among authors: wiekowski m. Respir Res. 2024 Feb 28;25(1):107. doi: 10.1186/s12931-024-02670-z. Respir Res. 2024. PMID: 38419035 Free PMC article. Clinical Trial.
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis.
Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. Chan JR, et al. Among authors: wiekowski m. J Exp Med. 2006 Nov 27;203(12):2577-87. doi: 10.1084/jem.20060244. Epub 2006 Oct 30. J Exp Med. 2006. PMID: 17074928 Free PMC article.
The pyrimidinergic P2Y6 receptor mediates a novel release of proinflammatory cytokines and chemokines in monocytic cells stimulated with UDP.
Cox MA, Gomes B, Palmer K, Du K, Wiekowski M, Wilburn B, Petro M, Chou CC, Desquitado C, Schwarz M, Lunn C, Lundell D, Narula SK, Zavodny PJ, Jenh CH. Cox MA, et al. Among authors: wiekowski m. Biochem Biophys Res Commun. 2005 May 6;330(2):467-73. doi: 10.1016/j.bbrc.2005.03.004. Biochem Biophys Res Commun. 2005. PMID: 15796906
The chemokine receptor D6 limits the inflammatory response in vivo.
Jamieson T, Cook DN, Nibbs RJ, Rot A, Nixon C, McLean P, Alcami A, Lira SA, Wiekowski M, Graham GJ. Jamieson T, et al. Among authors: wiekowski m. Nat Immunol. 2005 Apr;6(4):403-11. doi: 10.1038/ni1182. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750596 Free article.
41 results