Chai W - Search Results

1

Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance.

Sampathi S, Bhusari A, Shen B, Chai W. Sampathi S, et al. Among authors: chai w. J Biol Chem. 2009 Feb 6;284(6):3682-90. doi: 10.1074/jbc.M805362200. Epub 2008 Dec 9. J Biol Chem. 2009. PMID: 19068479 Free PMC article.

2

Human Ku70/80 associates physically with telomerase through interaction with hTERT.

Chai W, Ford LP, Lenertz L, Wright WE, Shay JW. Chai W, et al. J Biol Chem. 2002 Dec 6;277(49):47242-7. doi: 10.1074/jbc.M208542200. Epub 2002 Oct 10. J Biol Chem. 2002. PMID: 12377759 Free article.

3

Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection.

Dai X, Huang C, Bhusari A, Sampathi S, Schubert K, Chai W. Dai X, et al. Among authors: chai w. EMBO J. 2010 Aug 18;29(16):2788-801. doi: 10.1038/emboj.2010.156. Epub 2010 Jul 16. EMBO J. 2010. PMID: 20639858 Free PMC article.

4

Telomere replication: poised but puzzling.

Sampathi S, Chai W. Sampathi S, et al. Among authors: chai w. J Cell Mol Med. 2011 Jan;15(1):3-13. doi: 10.1111/j.1582-4934.2010.01220.x. J Cell Mol Med. 2011. PMID: 21122064 Free PMC article. Review.

5

Mapping the FEN1 interaction domain with hTERT.

Sampathi S, Chai W. Sampathi S, et al. Among authors: chai w. Biochem Biophys Res Commun. 2011 Apr 1;407(1):34-8. doi: 10.1016/j.bbrc.2011.02.087. Epub 2011 Feb 21. Biochem Biophys Res Commun. 2011. PMID: 21345332 Free PMC article.

6

CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase.

Dai X, Huang C, Chai W. Dai X, et al. Among authors: chai w. Cell Cycle. 2012 Aug 15;11(16):3079-86. doi: 10.4161/cc.21472. Epub 2012 Aug 8. Cell Cycle. 2012. PMID: 22871736 Free PMC article.

7

Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in.

Huang C, Dai X, Chai W. Huang C, et al. Among authors: chai w. Cell Res. 2012 Dec;22(12):1681-95. doi: 10.1038/cr.2012.132. Epub 2012 Sep 11. Cell Res. 2012. PMID: 22964711 Free PMC article.

8

Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity.

Lin W, Sampathi S, Dai H, Liu C, Zhou M, Hu J, Huang Q, Campbell J, Shin-Ya K, Zheng L, Chai W, Shen B. Lin W, et al. Among authors: chai w. EMBO J. 2013 May 15;32(10):1425-39. doi: 10.1038/emboj.2013.88. Epub 2013 Apr 19. EMBO J. 2013. PMID: 23604072 Free PMC article.

9

DNA2, a new player in telomere maintenance and tumor suppression.

Chai W, Zheng L, Shen B. Chai W, et al. Cell Cycle. 2013 Jul 1;12(13):1985-6. doi: 10.4161/cc.25306. Epub 2013 Jun 10. Cell Cycle. 2013. PMID: 23759580 Free PMC article. No abstract available.

10

The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.

Chung L, Onyango D, Guo Z, Jia P, Dai H, Liu S, Zhou M, Lin W, Pang I, Li H, Yuan YC, Huang Q, Zheng L, Lopes J, Nicolas A, Chai W, Raz D, Reckamp KL, Shen B. Chung L, et al. Among authors: chai w. Oncogene. 2015 Feb 12;34(7):902-11. doi: 10.1038/onc.2014.19. Epub 2014 Mar 10. Oncogene. 2015. PMID: 24608430 Free PMC article.

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