Nijnik A - Search Results

1

The roles of cathelicidin LL-37 in immune defences and novel clinical applications.

Nijnik A, Hancock RE. Nijnik A, et al. Curr Opin Hematol. 2009 Jan;16(1):41-7. doi: 10.1097/moh.0b013e32831ac517. Curr Opin Hematol. 2009. PMID: 19068548 Review.

2

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.

Kindrachuk J, Jenssen H, Elliott M, Townsend R, Nijnik A, Lee SF, Gerdts V, Babiuk LA, Halperin SA, Hancock RE. Kindrachuk J, et al. Among authors: nijnik a. Vaccine. 2009 Jul 23;27(34):4662-71. doi: 10.1016/j.vaccine.2009.05.094. Epub 2009 Jun 17. Vaccine. 2009. PMID: 19539585

3

Intracellular receptor for human host defense peptide LL-37 in monocytes.

Mookherjee N, Lippert DN, Hamill P, Falsafi R, Nijnik A, Kindrachuk J, Pistolic J, Gardy J, Miri P, Naseer M, Foster LJ, Hancock RE. Mookherjee N, et al. Among authors: nijnik a. J Immunol. 2009 Aug 15;183(4):2688-96. doi: 10.4049/jimmunol.0802586. Epub 2009 Jul 15. J Immunol. 2009. PMID: 19605696

4

Potential of immunomodulatory host defense peptides as novel anti-infectives.

Easton DM, Nijnik A, Mayer ML, Hancock RE. Easton DM, et al. Among authors: nijnik a. Trends Biotechnol. 2009 Oct;27(10):582-90. doi: 10.1016/j.tibtech.2009.07.004. Epub 2009 Aug 14. Trends Biotechnol. 2009. PMID: 19683819 Free PMC article. Review.

5

Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs.

Nijnik A, Pistolic J, Wyatt A, Tam S, Hancock RE. Nijnik A, et al. J Immunol. 2009 Nov 1;183(9):5788-98. doi: 10.4049/jimmunol.0901491. Epub 2009 Oct 7. J Immunol. 2009. PMID: 19812202

6

Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.

Nijnik A, Madera L, Ma S, Waldbrook M, Elliott MR, Easton DM, Mayer ML, Mullaly SC, Kindrachuk J, Jenssen H, Hancock RE. Nijnik A, et al. J Immunol. 2010 Mar 1;184(5):2539-50. doi: 10.4049/jimmunol.0901813. Epub 2010 Jan 27. J Immunol. 2010. PMID: 20107187

7

Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds.

Amatngalim GD, Nijnik A, Hiemstra PS, Hancock RE. Amatngalim GD, et al. Among authors: nijnik a. Inflammation. 2011 Oct;34(5):412-25. doi: 10.1007/s10753-010-9248-6. Inflammation. 2011. PMID: 20811938

8

The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.

Nijnik A, Clare S, Hale C, Raisen C, McIntyre RE, Yusa K, Everitt AR, Mottram L, Podrini C, Lucas M, Estabel J, Goulding D; Sanger Institute Microarray Facility; Sanger Mouse Genetics Project; Adams N, Ramirez-Solis R, White JK, Adams DJ, Hancock RE, Dougan G. Nijnik A, et al. Blood. 2012 Feb 9;119(6):1370-9. doi: 10.1182/blood-2011-05-352666. Epub 2011 Dec 19. Blood. 2012. PMID: 22184403 Free article.

9

The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.

Nijnik A, Pistolic J, Cho P, Filewod NC, Falsafi R, Ramin A, Harder KW, Hancock RE. Nijnik A, et al. J Leukoc Biol. 2012 Apr;91(4):599-607. doi: 10.1189/jlb.0411191. Epub 2012 Jan 13. J Leukoc Biol. 2012. PMID: 22246800 Free PMC article. Clinical Trial.

10

Modulating immunity as a therapy for bacterial infections.

Hancock RE, Nijnik A, Philpott DJ. Hancock RE, et al. Among authors: nijnik a. Nat Rev Microbiol. 2012 Mar 16;10(4):243-54. doi: 10.1038/nrmicro2745. Nat Rev Microbiol. 2012. PMID: 22421877 Review.

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