Okamura M - Search Results

1

Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest.

Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T. Dan S, et al. Among authors: okamura m. Biochem Biophys Res Commun. 2009 Jan 30;379(1):104-9. doi: 10.1016/j.bbrc.2008.12.015. Epub 2008 Dec 16. Biochem Biophys Res Commun. 2009. PMID: 19094964

2

Antiangiogenic effect of ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor.

Kong D, Okamura M, Yoshimi H, Yamori T. Kong D, et al. Among authors: okamura m. Eur J Cancer. 2009 Mar;45(5):857-65. doi: 10.1016/j.ejca.2008.12.007. Epub 2009 Jan 12. Eur J Cancer. 2009. PMID: 19144509

3

Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations.

Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T. Dan S, et al. Among authors: okamura m. Cancer Res. 2010 Jun 15;70(12):4982-94. doi: 10.1158/0008-5472.CAN-09-4172. Epub 2010 Jun 8. Cancer Res. 2010. PMID: 20530683

4

Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.

Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi S, Enami J, Yamori T, Okayasu R. Anzai K, et al. Among authors: okamura m. Cancer Sci. 2011 Jun;102(6):1176-80. doi: 10.1111/j.1349-7006.2011.01916.x. Epub 2011 Apr 4. Cancer Sci. 2011. PMID: 21352422 Free PMC article.

5

ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo.

Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T. Dan S, et al. Among authors: okamura m. Eur J Cancer. 2012 Apr;48(6):936-43. doi: 10.1016/j.ejca.2011.10.006. Epub 2011 Nov 14. Eur J Cancer. 2012. PMID: 22088482

6

AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy.

Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T. Ohashi Y, et al. Among authors: okamura m. J Biol Chem. 2012 Feb 3;287(6):3885-97. doi: 10.1074/jbc.M111.316125. Epub 2011 Dec 9. J Biol Chem. 2012. PMID: 22158626 Free PMC article.

7

Development of an immunohistochemical protein quantification system in conjunction with tissue microarray technology for identifying predictive biomarkers for phosphatidylinositol 3-kinase inhibitors.

Isoyama S, Yoshimi H, Dan S, Okamura M, Seki M, Irimura T, Yamori T. Isoyama S, et al. Among authors: okamura m. Biol Pharm Bull. 2012;35(9):1607-13. doi: 10.1248/bpb.b12-00327. Biol Pharm Bull. 2012. PMID: 22975517 Free article.

8

Thiophene-3-carboxamide analogue of annonaceous acetogenins as antitumor drug lead.

Kojima N, Fushimi T, Tatsukawa T, Tanaka T, Okamura M, Akatsuka A, Yamori T, Dan S, Iwasaki H, Yamashita M. Kojima N, et al. Among authors: okamura m. Eur J Med Chem. 2014 Oct 30;86:684-9. doi: 10.1016/j.ejmech.2014.09.026. Epub 2014 Sep 9. Eur J Med Chem. 2014. PMID: 25226228

9

Basal expression of insulin-like growth factor 1 receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474.

Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S. Isoyama S, et al. Among authors: okamura m. Cancer Sci. 2015 Feb;106(2):171-8. doi: 10.1111/cas.12582. Epub 2015 Jan 16. Cancer Sci. 2015. PMID: 25483727 Free PMC article.

10

Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription.

Takemoto Y, Ito A, Niwa H, Okamura M, Fujiwara T, Hirano T, Handa N, Umehara T, Sonoda T, Ogawa K, Tariq M, Nishino N, Dan S, Kagechika H, Yamori T, Yokoyama S, Yoshida M. Takemoto Y, et al. Among authors: okamura m. J Med Chem. 2016 Apr 28;59(8):3650-60. doi: 10.1021/acs.jmedchem.5b01732. Epub 2016 Apr 18. J Med Chem. 2016. PMID: 27088648

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