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Common variants in the NLRP3 region contribute to Crohn's disease susceptibility.
Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, Vermeire S, Hudson TJ, Franchimont D. Villani AC, et al. Among authors: sarfati m. Nat Genet. 2009 Jan;41(1):71-6. doi: 10.1038/ng.285. Epub 2008 Dec 21. Nat Genet. 2009. PMID: 19098911 Free PMC article.
CD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNF.
Baba N, Van VQ, Wakahara K, Rubio M, Fortin G, Panzini B, Soucy G, Wassef R, Richard C, Tamaz R, Lahaie R, Bernard EJ, Caussignac Y, Leduc R, Lougnarath R, Bergeron C, Racicot MA, Bergeron F, Panzini MA, Demetter P, Franchimont D, Schäkel K, Weckbecker G, Kolbinger F, Heusser C, Huber T, Welzenbach K, Sarfati M. Baba N, et al. Among authors: sarfati m. J Exp Med. 2013 Jun 3;210(6):1251-63. doi: 10.1084/jem.20122037. Epub 2013 May 13. J Exp Med. 2013. PMID: 23669395 Free PMC article.
CD28 co-stimulation down regulates Th17 development.
Bouguermouh S, Fortin G, Baba N, Rubio M, Sarfati M. Bouguermouh S, et al. Among authors: sarfati m. PLoS One. 2009;4(3):e5087. doi: 10.1371/journal.pone.0005087. Epub 2009 Mar 31. PLoS One. 2009. PMID: 19333372 Free PMC article.
216 results