Kane C - Search Results

1

Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function.

Carvalho L, Sun J, Kane C, Marshall F, Krawczyk C, Pearce EJ. Carvalho L, et al. Among authors: kane c. Immunology. 2009 Jan;126(1):28-34. doi: 10.1111/j.1365-2567.2008.03008.x. Immunology. 2009. PMID: 19120496 Free PMC article. Review.

2

Helminth antigens modulate TLR-initiated dendritic cell activation.

Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA, Pearce EJ. Kane CM, et al. J Immunol. 2004 Dec 15;173(12):7454-61. doi: 10.4049/jimmunol.173.12.7454. J Immunol. 2004. PMID: 15585871

3

Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation.

Artis D, Kane CM, Fiore J, Zaph C, Shapira S, Joyce K, Macdonald A, Hunter C, Scott P, Pearce EJ. Artis D, et al. Among authors: kane cm. J Immunol. 2005 Jun 1;174(11):7154-9. doi: 10.4049/jimmunol.174.11.7154. J Immunol. 2005. PMID: 15905559

4

Regulation of dendritic cell function by pathogen-derived molecules plays a key role in dictating the outcome of the adaptive immune response.

Pearce EJ, Kane CM, Sun J. Pearce EJ, et al. Chem Immunol Allergy. 2006;90:82-90. doi: 10.1159/000088882. Chem Immunol Allergy. 2006. PMID: 16210904 Review.

5

Schistosoma mansoni egg antigen-mediated modulation of Toll-like receptor (TLR)-induced activation occurs independently of TLR2, TLR4, and MyD88.

Kane CM, Jung E, Pearce EJ. Kane CM, et al. Infect Immun. 2008 Dec;76(12):5754-9. doi: 10.1128/IAI.00497-08. Epub 2008 Sep 29. Infect Immun. 2008. PMID: 18824534 Free PMC article.

6

Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses.

Cervi L, MacDonald AS, Kane C, Dzierszinski F, Pearce EJ. Cervi L, et al. Among authors: kane c. J Immunol. 2004 Feb 15;172(4):2016-20. doi: 10.4049/jimmunol.172.4.2016. J Immunol. 2004. PMID: 14764665

7

IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction.

Barlow JL, Peel S, Fox J, Panova V, Hardman CS, Camelo A, Bucks C, Wu X, Kane CM, Neill DR, Flynn RJ, Sayers I, Hall IP, McKenzie AN. Barlow JL, et al. Among authors: kane cm. J Allergy Clin Immunol. 2013 Oct;132(4):933-41. doi: 10.1016/j.jaci.2013.05.012. Epub 2013 Jun 27. J Allergy Clin Immunol. 2013. PMID: 23810766

8

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.

Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, Bucks C, Kane CM, Fallon PG, Pannell R, Jolin HE, McKenzie AN. Neill DR, et al. Among authors: kane cm. Nature. 2010 Apr 29;464(7293):1367-70. doi: 10.1038/nature08900. Epub 2010 Mar 3. Nature. 2010. PMID: 20200518 Free PMC article.

9

Inhalation delivery of protein therapeutics.

Kane C, O'Neil K, Conk M, Picha K. Kane C, et al. Inflamm Allergy Drug Targets. 2013 Apr;12(2):81-7. doi: 10.2174/1871528111312020002. Inflamm Allergy Drug Targets. 2013. PMID: 23517644 Review.

10

Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics.

Jacobs SA, Gibbs AC, Conk M, Yi F, Maguire D, Kane C, O'Neil KT. Jacobs SA, et al. Among authors: kane c. Protein Eng Des Sel. 2015 Oct;28(10):385-93. doi: 10.1093/protein/gzv040. Epub 2015 Aug 13. Protein Eng Des Sel. 2015. PMID: 26275855

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