Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

283 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug.
Hayashi S, Hirao A, Imai A, Nakamura H, Murata Y, Ohashi K, Nakata E. Hayashi S, et al. Among authors: hirao a. J Med Chem. 2009 Feb 12;52(3):610-25. doi: 10.1021/jm7012979. J Med Chem. 2009. PMID: 19125610
Discovery of 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: integrated drug-design and structure-activity relationships for orally potent, metabolically stable and potential-risk reduced novel non-peptide nociceptin/orphanin FQ receptor agonist as antianxiety drug.
Hayashi S, Hirao A, Nakamura H, Yamamura K, Mizuno K, Yamashita H. Hayashi S, et al. Among authors: hirao a. Chem Biol Drug Des. 2009 Oct;74(4):369-81. doi: 10.1111/j.1747-0285.2009.00872.x. Epub 2009 Aug 18. Chem Biol Drug Des. 2009. PMID: 19691471
N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.
Mori H, Tonai-Kachi H, Ochi Y, Taniguchi Y, Ohshiro H, Takahashi N, Aihara T, Hirao A, Kato T, Sakakibara M, Kurebayashi Y. Mori H, et al. Among authors: hirao a. J Pharmacol Exp Ther. 2009 Feb;328(2):671-9. doi: 10.1124/jpet.108.146415. Epub 2008 Nov 3. J Pharmacol Exp Ther. 2009. PMID: 18981288
[Basic and applied science of chrononutrition].
Shibata S, Hirao A. Shibata S, et al. Among authors: hirao a. Nihon Yakurigaku Zasshi. 2011 Mar;137(3):110-4. doi: 10.1254/fpj.137.110. Nihon Yakurigaku Zasshi. 2011. PMID: 21415557 Review. Japanese. No abstract available.
283 results