Balle T - Search Results

1

Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.

Armishaw C, Jensen AA, Balle T, Clark RJ, Harpsøe K, Skonberg C, Liljefors T, Strømgaard K. Armishaw C, et al. Among authors: balle t. J Biol Chem. 2009 Apr 3;284(14):9498-512. doi: 10.1074/jbc.M806136200. Epub 2009 Jan 8. J Biol Chem. 2009. PMID: 19131337 Free PMC article.

2

Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.

Hansen CP, Jensen AA, Christensen JK, Balle T, Liljefors T, Frølund B. Hansen CP, et al. Among authors: balle t. J Med Chem. 2008 Dec 11;51(23):7380-95. doi: 10.1021/jm701625v. J Med Chem. 2008. PMID: 18989912

3

Carbamoylcholine analogs as nicotinic acetylcholine receptor agonists--structural modifications of 3-(dimethylamino)butyl dimethylcarbamate (DMABC).

Hansen CP, Jensen AA, Balle T, Bitsch-Jensen K, Hassan MM, Liljefors T, Frølund B. Hansen CP, et al. Among authors: balle t. Bioorg Med Chem Lett. 2009 Jan 1;19(1):87-91. doi: 10.1016/j.bmcl.2008.11.011. Epub 2008 Nov 7. Bioorg Med Chem Lett. 2009. PMID: 19027295

4

Ginkgolide X is a potent antagonist of anionic Cys-loop receptors with a unique selectivity profile at glycine receptors.

Jensen AA, Bergmann ML, Sander T, Balle T. Jensen AA, et al. Among authors: balle t. J Biol Chem. 2010 Mar 26;285(13):10141-10153. doi: 10.1074/jbc.M109.079319. Epub 2010 Jan 27. J Biol Chem. 2010. PMID: 20106969 Free PMC article.

5

Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed.

Rohde LA, Ahring PK, Jensen ML, Nielsen EØ, Peters D, Helgstrand C, Krintel C, Harpsøe K, Gajhede M, Kastrup JS, Balle T. Rohde LA, et al. Among authors: balle t. J Biol Chem. 2012 Feb 3;287(6):4248-59. doi: 10.1074/jbc.M111.292243. Epub 2011 Dec 13. J Biol Chem. 2012. PMID: 22170047 Free PMC article.

6

Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site.

Trattnig SM, Harpsøe K, Thygesen SB, Rahr LM, Ahring PK, Balle T, Jensen AA. Trattnig SM, et al. Among authors: balle t. J Biol Chem. 2012 Jul 20;287(30):25241-54. doi: 10.1074/jbc.M112.360370. Epub 2012 May 15. J Biol Chem. 2012. PMID: 22589534 Free PMC article.

7

Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors.

Harpsøe K, Hald H, Timmermann DB, Jensen ML, Dyhring T, Nielsen EØ, Peters D, Balle T, Gajhede M, Kastrup JS, Ahring PK. Harpsøe K, et al. Among authors: balle t. J Biol Chem. 2013 Jan 25;288(4):2559-70. doi: 10.1074/jbc.M112.436337. Epub 2012 Dec 10. J Biol Chem. 2013. PMID: 23229547 Free PMC article.

8

Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.

Crestey F, Jensen AA, Borch M, Andreasen JT, Andersen J, Balle T, Kristensen JL. Crestey F, et al. Among authors: balle t. J Med Chem. 2013 Dec 12;56(23):9673-82. doi: 10.1021/jm4013592. Epub 2013 Nov 21. J Med Chem. 2013. PMID: 24187998

9

Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations.

de la Fuente Revenga M, Balle T, Jensen AA, Frølund B. de la Fuente Revenga M, et al. Among authors: balle t. Eur J Med Chem. 2015 Sep 18;102:352-62. doi: 10.1016/j.ejmech.2015.07.029. Epub 2015 Jul 17. Eur J Med Chem. 2015. PMID: 26298493

10

Regioselectivity in lithiation of 1-methylpyrazole: experimental, density functional theory and multinuclear NMR study.

Balle T, Begtrup M, Jaroszewski JW, Liljefors T, Norrby PO. Balle T, et al. Org Biomol Chem. 2006 Apr 7;4(7):1261-7. doi: 10.1039/b517607g. Epub 2006 Feb 3. Org Biomol Chem. 2006. PMID: 16557314

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