Ahmad R - Search Results

1

Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease.

Blackinton J, Kumaran R, van der Brug MP, Ahmad R, Olson L, Galter D, Lees A, Bandopadhyay R, Cookson MR. Blackinton J, et al. Among authors: ahmad r. Neurosci Lett. 2009 Mar 6;452(1):8-11. doi: 10.1016/j.neulet.2008.12.053. Epub 2009 Jan 6. Neurosci Lett. 2009. PMID: 19146923 Free PMC article.

2

Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization.

Blackinton J, Ahmad R, Miller DW, van der Brug MP, Canet-Avilés RM, Hague SM, Kaleem M, Cookson MR. Blackinton J, et al. Among authors: ahmad r. Brain Res Mol Brain Res. 2005 Mar 24;134(1):76-83. doi: 10.1016/j.molbrainres.2004.09.004. Brain Res Mol Brain Res. 2005. PMID: 15790532

3

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.

van der Brug MP, Blackinton J, Chandran J, Hao LY, Lal A, Mazan-Mamczarz K, Martindale J, Xie C, Ahmad R, Thomas KJ, Beilina A, Gibbs JR, Ding J, Myers AJ, Zhan M, Cai H, Bonini NM, Gorospe M, Cookson MR. van der Brug MP, et al. Among authors: ahmad r. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10244-9. doi: 10.1073/pnas.0708518105. Epub 2008 Jul 14. Proc Natl Acad Sci U S A. 2008. PMID: 18626009 Free PMC article.

4

Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1.

Blackinton J, Lakshminarasimhan M, Thomas KJ, Ahmad R, Greggio E, Raza AS, Cookson MR, Wilson MA. Blackinton J, et al. Among authors: ahmad r. J Biol Chem. 2009 Mar 6;284(10):6476-85. doi: 10.1074/jbc.M806599200. Epub 2009 Jan 5. J Biol Chem. 2009. PMID: 19124468 Free PMC article.

5

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.

Miller DW, Ahmad R, Hague S, Baptista MJ, Canet-Aviles R, McLendon C, Carter DM, Zhu PP, Stadler J, Chandran J, Klinefelter GR, Blackstone C, Cookson MR. Miller DW, et al. Among authors: ahmad r. J Biol Chem. 2003 Sep 19;278(38):36588-95. doi: 10.1074/jbc.M304272200. Epub 2003 Jul 8. J Biol Chem. 2003. PMID: 12851414 Free article.

6

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.

Canet-Avilés RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. Canet-Avilés RM, et al. Among authors: ahmad r. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9103-8. doi: 10.1073/pnas.0402959101. Epub 2004 Jun 4. Proc Natl Acad Sci U S A. 2004. PMID: 15181200 Free PMC article.

7

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.

Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR. Beilina A, et al. Among authors: ahmad r. Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5703-8. doi: 10.1073/pnas.0500617102. Epub 2005 Apr 11. Proc Natl Acad Sci U S A. 2005. PMID: 15824318 Free PMC article.

8

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.

Greggio E, Jain S, Kingsbury A, Bandopadhyay R, Lewis P, Kaganovich A, van der Brug MP, Beilina A, Blackinton J, Thomas KJ, Ahmad R, Miller DW, Kesavapany S, Singleton A, Lees A, Harvey RJ, Harvey K, Cookson MR. Greggio E, et al. Among authors: ahmad r. Neurobiol Dis. 2006 Aug;23(2):329-41. doi: 10.1016/j.nbd.2006.04.001. Epub 2006 Jun 5. Neurobiol Dis. 2006. PMID: 16750377

9

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

Greggio E, Lewis PA, van der Brug MP, Ahmad R, Kaganovich A, Ding J, Beilina A, Baker AK, Cookson MR. Greggio E, et al. Among authors: ahmad r. J Neurochem. 2007 Jul;102(1):93-102. doi: 10.1111/j.1471-4159.2007.04523.x. Epub 2007 Mar 29. J Neurochem. 2007. PMID: 17394548 Free article.

10

Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines.

Baptista MJ, O'Farrell C, Daya S, Ahmad R, Miller DW, Hardy J, Farrer MJ, Cookson MR. Baptista MJ, et al. Among authors: ahmad r. J Neurochem. 2003 May;85(4):957-68. doi: 10.1046/j.1471-4159.2003.01742.x. J Neurochem. 2003. PMID: 12716427 Free article.

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