Geacintov N - Search Results

1

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals.

Shachar S, Ziv O, Avkin S, Adar S, Wittschieben J, Reissner T, Chaney S, Friedberg EC, Wang Z, Carell T, Geacintov N, Livneh Z. Shachar S, et al. Among authors: geacintov n. EMBO J. 2009 Feb 18;28(4):383-93. doi: 10.1038/emboj.2008.281. Epub 2009 Jan 15. EMBO J. 2009. PMID: 19153606 Free PMC article.

2

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.

Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. Hendel A, et al. Among authors: geacintov ne. PLoS Genet. 2011 Sep;7(9):e1002262. doi: 10.1371/journal.pgen.1002262. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931560 Free PMC article.

3

Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells.

Izhar L, Ziv O, Cohen IS, Geacintov NE, Livneh Z. Izhar L, et al. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1462-9. doi: 10.1073/pnas.1216894110. Epub 2013 Mar 25. Proc Natl Acad Sci U S A. 2013. PMID: 23530190 Free PMC article.

4

Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin.

Ziv O, Zeisel A, Mirlas-Neisberg N, Swain U, Nevo R, Ben-Chetrit N, Martelli MP, Rossi R, Schiesser S, Canman CE, Carell T, Geacintov NE, Falini B, Domany E, Livneh Z. Ziv O, et al. Among authors: geacintov ne. Nat Commun. 2014 Nov 25;5:5437. doi: 10.1038/ncomms6437. Nat Commun. 2014. PMID: 25421715 Free PMC article.

5

Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa.

Avkin S, Goldsmith M, Velasco-Miguel S, Geacintov N, Friedberg EC, Livneh Z. Avkin S, et al. Among authors: geacintov n. J Biol Chem. 2004 Dec 17;279(51):53298-305. doi: 10.1074/jbc.M409155200. Epub 2004 Oct 9. J Biol Chem. 2004. PMID: 15475561 Free article.

6

p53 and p21 regulate error-prone DNA repair to yield a lower mutation load.

Avkin S, Sevilya Z, Toube L, Geacintov N, Chaney SG, Oren M, Livneh Z. Avkin S, et al. Among authors: geacintov n. Mol Cell. 2006 May 5;22(3):407-13. doi: 10.1016/j.molcel.2006.03.022. Mol Cell. 2006. PMID: 16678112 Free article.

7

Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta.

Hendel A, Ziv O, Gueranger Q, Geacintov N, Livneh Z. Hendel A, et al. Among authors: geacintov n. DNA Repair (Amst). 2008 Oct 1;7(10):1636-46. doi: 10.1016/j.dnarep.2008.06.008. Epub 2008 Aug 3. DNA Repair (Amst). 2008. PMID: 18634905 Free PMC article.

8

DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.

Ziv O, Geacintov N, Nakajima S, Yasui A, Livneh Z. Ziv O, et al. Among authors: geacintov n. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11552-7. doi: 10.1073/pnas.0812548106. Epub 2009 Jun 29. Proc Natl Acad Sci U S A. 2009. PMID: 19564618 Free PMC article.

9

TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer.

Swain U, Friedlander G, Sehrawat U, Sarusi-Portuguez A, Rotkopf R, Ebert C, Paz-Elizur T, Dikstein R, Carell T, Geacintov NE, Livneh Z. Swain U, et al. Among authors: geacintov ne. Int J Mol Sci. 2021 Jun 28;22(13):6957. doi: 10.3390/ijms22136957. Int J Mol Sci. 2021. PMID: 34203408 Free PMC article.

10

Repair of gaps opposite lesions by homologous recombination in mammalian cells.

Adar S, Izhar L, Hendel A, Geacintov N, Livneh Z. Adar S, et al. Among authors: geacintov n. Nucleic Acids Res. 2009 Sep;37(17):5737-48. doi: 10.1093/nar/gkp632. Epub 2009 Aug 4. Nucleic Acids Res. 2009. PMID: 19654238 Free PMC article.

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