Chen X - Search Results

1

Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products.

Diaz SL, Padler-Karavani V, Ghaderi D, Hurtado-Ziola N, Yu H, Chen X, Brinkman-Van der Linden EC, Varki A, Varki NM. Diaz SL, et al. Among authors: chen x. PLoS One. 2009;4(1):e4241. doi: 10.1371/journal.pone.0004241. Epub 2009 Jan 21. PLoS One. 2009. PMID: 19156207 Free PMC article.

2

Chemoenzymatic synthesis of CMP-sialic acid derivatives by a one-pot two-enzyme system: comparison of substrate flexibility of three microbial CMP-sialic acid synthetases.

Yu H, Yu H, Karpel R, Chen X. Yu H, et al. Among authors: chen x. Bioorg Med Chem. 2004 Dec 15;12(24):6427-35. doi: 10.1016/j.bmc.2004.09.030. Bioorg Med Chem. 2004. PMID: 15556760

3

Characterization of a bifunctional cytidine 5'-monophosphate N-acetylneuraminic acid synthetase cloned from Streptococcus agalactiae.

Yu H, Ryan W, Yu H, Chen X. Yu H, et al. Among authors: chen x. Biotechnol Lett. 2006 Jan;28(2):107-13. doi: 10.1007/s10529-005-4955-z. Biotechnol Lett. 2006. PMID: 16369694

4

Aldolase-catalyzed synthesis of beta-D-galp-(1-->9)-D-KDN: a novel acceptor for sialyltransferases.

Yu H, Chen X. Yu H, et al. Among authors: chen x. Org Lett. 2006 May 25;8(11):2393-6. doi: 10.1021/ol060736m. Org Lett. 2006. PMID: 16706534

5

High-throughput substrate specificity studies of sialidases by using chemoenzymatically synthesized sialoside libraries.

Chokhawala HA, Yu H, Chen X. Chokhawala HA, et al. Among authors: chen x. Chembiochem. 2007 Jan 22;8(2):194-201. doi: 10.1002/cbic.200600410. Chembiochem. 2007. PMID: 17195254 Free PMC article.

6

Disaccharides as sialic acid aldolase substrates: synthesis of disaccharides containing a sialic acid at the reducing end.

Huang S, Yu H, Chen X. Huang S, et al. Among authors: chen x. Angew Chem Int Ed Engl. 2007;46(13):2249-53. doi: 10.1002/anie.200604799. Angew Chem Int Ed Engl. 2007. PMID: 17309109 No abstract available.

7

Carbohydrate post-glycosylational modifications.

Yu H, Chen X. Yu H, et al. Among authors: chen x. Org Biomol Chem. 2007 Mar 21;5(6):865-72. doi: 10.1039/b700034k. Epub 2007 Feb 6. Org Biomol Chem. 2007. PMID: 17340000 Free PMC article.

8

One-pot three-enzyme chemoenzymatic approach to the synthesis of sialosides containing natural and non-natural functionalities.

Yu H, Chokhawala HA, Huang S, Chen X. Yu H, et al. Among authors: chen x. Nat Protoc. 2006;1(5):2485-92. doi: 10.1038/nprot.2006.401. Nat Protoc. 2006. PMID: 17406495 Free PMC article.

9

Efficient chemoenzymatic synthesis of biotinylated human serum albumin-sialoglycoside conjugates containing O-acetylated sialic acids.

Yu H, Chokhawala HA, Varki A, Chen X. Yu H, et al. Among authors: chen x. Org Biomol Chem. 2007 Aug 7;5(15):2458-63. doi: 10.1039/b706507h. Epub 2007 Jun 27. Org Biomol Chem. 2007. PMID: 17637967 Free PMC article.

10

NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus.

Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. Lewis AL, et al. Among authors: chen x. J Biol Chem. 2007 Sep 21;282(38):27562-71. doi: 10.1074/jbc.M700340200. Epub 2007 Jul 23. J Biol Chem. 2007. PMID: 17646166 Free PMC article.

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